Registration Dossier
Registration Dossier
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EC number: 206-056-4 | CAS number: 298-07-7
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: insufficient documented
Data source
Reference
- Reference Type:
- publication
- Title:
- Range-finding toxicity data: List VI
- Author:
- Smyth HF, Carpenter CP, Weil CS, Pozzani UC, Striegel JA
- Year:
- 1 962
- Bibliographic source:
- Am Ind Hyg Ass J 23, 95-107, 1962
Materials and methods
- Principles of method if other than guideline:
- Groups of 6 male or female rats were exposed to concentrated vapour of bis(2-ethylhexyl) hydrogen phosphate for up to 8 hours.
- GLP compliance:
- no
- Test type:
- other: inhalation hazard test
Test material
- Reference substance name:
- Bis(2-ethylhexyl) hydrogen phosphate
- EC Number:
- 206-056-4
- EC Name:
- Bis(2-ethylhexyl) hydrogen phosphate
- Cas Number:
- 298-07-7
- Molecular formula:
- C16H35O4P
- IUPAC Name:
- bis(2-ethylhexyl) hydrogen phosphate
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation: vapour
- Type of inhalation exposure:
- whole body
- Vehicle:
- clean air
- Analytical verification of test atmosphere concentrations:
- no
- Concentrations:
- Rats were exposed to concentrated vapour of the test substance - but no analytical data were presented in the publication.
A saturated chamber atmosphere has a concentration of 1300 mg/m³ according the BUA report no 172. - No. of animals per sex per dose:
- 6 male or six female animals/exposure period
- Control animals:
- no
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LC0
- Effect level:
- > 1 300 mg/m³ air (nominal)
- Based on:
- test mat.
- Exp. duration:
- 8 h
Any other information on results incl. tables
After an exposure of 8 hours in a concentrated vapours atmosphere no animals died within 14 days.
Applicant's summary and conclusion
- Executive summary:
No animals died within 14 days after an exposure of 8 hours in a concentrated test atmosphere.
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