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EC number: 211-067-2 | CAS number: 629-03-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1998
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study without detailed documentation
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 998
- Report date:
- 1998
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Deviations:
- not specified
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Dibromo-1,6-hexane
- IUPAC Name:
- Dibromo-1,6-hexane
- Details on test material:
- No data indicated in the report.
Constituent 1
Study design
- Oxygen conditions:
- not specified
- Inoculum or test system:
- not specified
- Duration of test (contact time):
- 28 d
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Remarks:
- - BOD (mg O2 consummed by mg of substance)
- Details on study design:
- The report refers to the protocol described in the annexe C.4-E of the Directive 92/69/CEE. This protocol is in accordance with the OECD guideline N°301D adopted 17/07/1992.
Reference substance
- Reference substance:
- other: Sodium benzoate
Results and discussion
- Test performance:
- Validity criteria of the test:
- The difference between the extreme values of the replicates obtained in the test serie (Serie 2) is less than 20%;
- The percentage of degradation of the reference material the serie of inoculum control (Serie 4) is greater than 60% in 14 days;
- The degradation of th ereference material in the serie of inhibition control (serie 3) is greater than 25% during the first 14 days: the degradation of reference substance was not inhibited by the presence of the test substance;
- The loss of oxygen in the blank serie (Serie 1) containing the inoculum did not exceed 1.5mg/ l dissolved O2 after 28 days;
- The residual oxygen concentration in the test flasks was always greater than 0.5mg/ l throughout the test period.
% Degradationopen allclose all
- Parameter:
- % degradation (O2 consumption)
- Remarks:
- - expressed in: mg O2 consumed by mg of substance
- Value:
- 0
- Sampling time:
- 0 d
- Remarks on result:
- other: Milieu + inoculum + substance
- Parameter:
- % degradation (O2 consumption)
- Remarks:
- - expressed in: mg O2 consumed by mg of substance
- Value:
- 23
- Sampling time:
- 7 d
- Remarks on result:
- other: Milieu + inoculum + substance
- Parameter:
- % degradation (O2 consumption)
- Remarks:
- - expressed in: mg O2 consumed by mg of substance
- Value:
- 35
- Sampling time:
- 14 d
- Remarks on result:
- other: Milieu + inoculum + substance
- Parameter:
- % degradation (O2 consumption)
- Remarks:
- - expressed in: mg O2 consumed by mg of substance
- Value:
- 72
- Sampling time:
- 21 d
- Remarks on result:
- other: Milieu + inoculum + substance
- Parameter:
- % degradation (O2 consumption)
- Remarks:
- - expressed in: mg O2 consumed by mg of substance
- Value:
- 78
- Sampling time:
- 28 d
- Remarks on result:
- other: Milieu + inoculum + substance
BOD5 / COD results
BOD5 / COD
- Parameter:
- COD
- Value:
- 1.11 other: mgO2/mg test. mat.
Any other information on results incl. tables
Tables with the complete results:
COD ou DThO (mgO2/mg)
COD ou DThO | (mgO2/mg) |
Dibromo-1,6-hexane | 1.11 |
Sodium benzoate | 1.67 |
Serie 3 | 1.34 |
BOD specific ( mg O2 consumed/ mg test. mat.)
Time (days) | 0 | 7 | 14 | 21 | 28 |
Serie 2 (substance) | 0.00 | 0.25 | 0.39 | 0.81 | 0.87 |
Serie 3 (inhibition control) | 0.00 | 0.60 | 0.75 | 0.98 | 1.07 |
Serie 4 (reference) | 0.00 | 1.33 | 1.38 | 1.33 | 1.44 |
Biodegradability (mean)
Time (days) | 0 | 7 | 14 | 21 | 28 |
Serie 2 (substance) | 0% | 23% | 35% | 72% | 78% |
Serie 3 (inhibition control) | 0% | 45% | 56% | 74% | 80% |
Serie 4 (reference) | 0% | 80% | 83% | 80% | 86% |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable, but failing 10-day window
- Conclusions:
- Under the conditions of the test performed under 301D OECD guideline, the biodegradation percentage of dibromo-1,6-hexane was 78% in 28 days (end of testing). Within the 10 days windows, it was about 32%. Within 14 days to the commencement of the testing, the percentage of degradation has reached 35%.
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