6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one, 2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-7-methyl-, (2S,3S,3aR,9aS)-

Flammability

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

substances / mixtures which in contact with water emit flammable gases

Type of information:

calculation (if not (Q)SAR)

Adequacy of study:

key study

Study period:

05 May - 15 October 2008

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.12 (Flammability (Contact with Water))

Deviations:

no

Principles of method if other than guideline:

A test substance is considered highly flammable, when it ignites spontaneously when coming into contact with water or damp air, or evolves flammable gas at a rate > 1 I/kg of the test substance per hour.

The structure of the test substance does not contain groups that might lead to the evolution of a dangerous amount of flammable gas when coming into contact with water or damp air. No metals, transition metals, boron or silicon are present. The impurities, present for :s; 0.3% in the test substance, were not taken into account but it is not to be expected that these have any influence.

GLP compliance:

yes (incl. QA statement)

Key result

Test procedure:

other: statement

Remarks on result:

not measured/tested

Statement on Flammability in contact with water:

The structures of the test substance do not contain groups that might lead to the evolution of a dangerous amount of flammable gas when coming into contact with water or damp air. No metals, transition metals, boron or silicon are present.

In conclusion, the test substance is not highly flammable in contact with water or damp air.

Interpretation of results:

non flammable

Remarks:

Migrated information

Conclusions:

The structure of the test substance does not contain groups that might lead to the evolution of a dangerous amount of flammable gas when coming into contact with water or damp air. No metals, transition metals, boron or silicon are present. The impurities, present for :s; 0.3% in the test substance, were not taken into account but it is not to be expected that these have any influence.

The test substance is not highly flammable in contact with water or damp air.

Reference 2

Endpoint:

flammable solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

05 May - 15 October 2008

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.10 (Flammability (Solids))

Deviations:

no

GLP compliance:

yes

Key result

Test procedure:

burning rate test: preliminary screening test

Remarks on result:

substance does not ignite and propagate combustion either by burning with flame or smouldering along 200 mm of the powder train within the 2 minutes test period

The flame of the gas burner did ignite the test substance pile. The test substance melted, emitted yellow sparks, burned with a yellow/bleu flame and turned into a charred residue. Grey fume was also observed. After removal of the ignition source, the flame extinguished immediately and no propagate combustion was observed.

Interpretation of results:

non flammable

Remarks:

Migrated information

Conclusions:

The preliminary screening test was performed for the determination of the flammability of the test substance. No propagate combustion of the test substance along 200 mm length of the pile within 4 minutes was observed. Bases on this, the test substance was not considered as highly flammable.

Reference 3

Endpoint:

pyrophoric solids

Remarks:

Pyrophoric liquids/solids (migrated from section 'Flammability')

Type of information:

calculation (if not (Q)SAR)

Adequacy of study:

key study

Study period:

05 May - 15 October 2008

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.13 (Pyrophoric Properties of Solids and Liquids)

Deviations:

no

GLP compliance:

yes

Key result

Test procedure:

ignition time on contact with air

Remarks:

Ignition on contact with air refers to either Pyrophoric solids or Pyrophoric liquids depending on physical state (migrated information).

Remarks on result:

no ignition on contact with air (not further specified)

Statement on Pyrophoric properties:

The molecular structure of the test substance does not contain any chemical groups that might lead to spontaneous ignition a short time after coming into contact with air. Furthermore, experience in handling during the flammability test shows that the test substance does not ignite spontaneously after coming in contact with air at room temperature.

In conclusion, the test substance is non-pyrophoric.

Interpretation of results:

non flammable

Remarks:

Migrated information

Conclusions:

The molecular structure of the test substance does not contain any chemical groups that might lead to spontaneous ignition a short time after coming into contact with air. The impurities, present for 0.3% in the test substance, were not taken into account but it is not to be expected that these have any influence.
Furthermore, experience in handling during this project shows that the test substance does not ignite spontaneously after coming in contact with air at room temperature.
The test substance is not pyrophoric.

Description of key information

The test substance is not considered as highly flammable.

The test substance is not highly flammable in contact with water or damp air.

The test substance is not pyrophoric.

Key value for chemical safety assessment

Flammability:

not classified

Justification for classification or non-classification

The preliminary screening test was performed for the determination of the flammability of the test substance. No propagate combustion of the test substance along 200 mm length of the pile within 4 minutes was observed. Bases on this, the test substance was not considered as highly flammable.

The structure of the test substance does not contain groups that might lead to the evolution of a dangerous amount of flammable gas when coming into contact with water or damp air. No metals, transition metals, boron or silicon are present. The impurities, present for :s; 0.3% in the test substance, were not taken into account but it is not to be expected that these have any influence.

The test substance is not highly flammable in contact with water or damp air.

The molecular structure of the test substance does not contain any chemical groups that might lead to spontaneous ignition a short time after coming into contact with air. The impurities, present for 0.3% in the test substance, were not taken into account but it is not to be expected that these have any influence.

Furthermore, experience in handling during this project shows that the test substance does not ignite spontaneously after coming in contact with air at room temperature.

The test substance is not pyrophoric.