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Diss Factsheets
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EC number: 904-790-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Report date:
- 2020
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Reaction mass of (24R)-ergost-5-en-3β-ol and stigmast-5-en-3-β-ol and stigmasta-5,22-dien-3-β-ol
- EC Number:
- 904-790-6
- Molecular formula:
- C28H48O; C29H50O; C29H48O
- IUPAC Name:
- Reaction mass of (24R)-ergost-5-en-3β-ol and stigmast-5-en-3-β-ol and stigmasta-5,22-dien-3-β-ol
Constituent 1
Study design
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Duration of test (contact time):
- 28 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 76.5 mg/L
- Based on:
- COD
- Initial conc.:
- 150 mg/L
- Based on:
- test mat.
- Details on study design:
- For the test concentration and for the negative control, 100 mL capacity conical glass flasks
capped with air permeable stoppers were used.
Six replicates for test concentration and six for negative control were prepared. At test start,
50 mL of test solutions were poured into the test flasks and inoculated with algae to obtain a
starting cell density of about 104 cells/mL.
For the test concentration and for the negative control, 100 mL capacity conical glass flasks
capped with air permeable stoppers were used.
Six replicates for test concentration and six for negative control were prepared. At test start,
50 mL of test solutions were poured into the test flasks and inoculated with algae to obtain a
starting cell density of about 104 cells/mL.
Temperature: 21.6-23.1 °C
Light conditions: darkness
Stirring: continuous
Results and discussion
% Degradationopen allclose all
- Parameter:
- % degradation (O2 consumption)
- Value:
- 126.1
- Sampling time:
- 28 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 61.4
- Sampling time:
- 10 d
- Details on results:
- The ThOD NH3 value was calculated to be equal to 1.67 mg O2/mg for reference item, Sodium benzoate, while COD value was assessed to be 0.51 mg O2/mg for the test item.
These values were used to calculate % biodegradation.
At the start and test end no nitrite and nitrate were present.
No significacnt degradation was observed in the abiotic control (equal to 5.2% at the test end).
The test item does not cause inhibitory effect on the microorganisms activity at the tested concentration. Actually, the toxicity control exceed the 25% pass level within the 14 days of exposure (81,3%).
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- At the end of the test the biodegradation was 126.1% (mean % values between two replicates).
Therefore, the test item was found to be ready and completely biodegradable under the conditions applied in a manometric respirometry test, since at the end of the 10-day window the biodegradation was 61.4% and a maximum biodegradation of 126.1% was found at the end of the test (mean % values between two replicates).
The test item showed no inhibitory effects on the microorganism activity at the tested concentration, as demonstrated by the biodegradation percentage in the toxicity cotrol exceeding the 25% pass level within 14 days of exposure (81.3%).
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