Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
(Q)SAR
Remarks:
VEGA QSAR Daphnia Magna LC50 48h (EPA) 1.0.7
Adequacy of study:
key study
Study period:
2021
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model, but not (completely) falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
VEGA QSAR Daphnia Magna LC50 48h (EPA) 1.0.7

Data source

Reference
Reference Type:
other: QSAR model
Title:
Daphnia acute toxicity AZELAMIDE MEA
Year:
2021
Bibliographic source:
VEGA QSAR Daphnia magna LC50 48h (EPA) 1.0.7
Report date:
2021

Materials and methods

Test guideline
Qualifier:
no guideline required
Principles of method if other than guideline:
VEGA QSAR Daphnia Magna LC50 48h (EPA) 1.0.7

Test material

Constituent 1
Chemical structure
Reference substance name:
9-[(2-hydroxyethyl)amino]-9-oxononanoic acid
Cas Number:
242132-61-2
Molecular formula:
C11H21NO4
IUPAC Name:
9-[(2-hydroxyethyl)amino]-9-oxononanoic acid
Test material form:
solid: granular

Test organisms

Test organisms (species):
Daphnia magna

Results and discussion

Effect concentrations
Key result
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
352.56 mg/L

Applicant's summary and conclusion

Conclusions:
Not classified as hazardous according to Regulation (EC) n. 1272/2008