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Diss Factsheets
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EC number: 950-463-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: Method for Testing the Biodegradability of Chemical Substances by Microrganisms stipulated in the Testing Methods for New Chemical Substances, Japan
- Deviations:
- no
- Principles of method if other than guideline:
- not applicable
- GLP compliance:
- yes
- Specific details on test material used for the study:
- Name: HES 10108 (supplied as Dow Corning® BY 16-122 B)
CAS No.: Not Listed
ID No.:HESI0108
Lot No.: 0008624816
Source: Dow Corning Corporation, Auburn, Michigan
Physical Description: Colorless liquid
Purity: 99.3%, used as 100%
Storage Conditions: Room Temperature
Expiration Date: 25 August 2017 - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- Activated sludge cultivated in the laboratory was used. On-site sludge samplimg was carried out at 10 locations (samples from surface water and surface soil of rivers, lakes and inland seas and return sludge from sewage plants). Activated sludge was prepared and maintained under laboratory conditions. For the test,, activated sludge which was cultivated for 18.5 hours after feeding with syntheticsewage was used.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Standard test conditions as outlined in the guidelines were used
- Reference substance:
- aniline
- Key result
- Parameter:
- % degradation (test mat. analysis)
- Value:
- 0
- Sampling time:
- 28 d
- Remarks on result:
- other:
- Remarks:
- The test item was not readily biodegradable under the test conditions
- Details on results:
- The average percentage biodegradation by BOD and that of the test item analytically were 2% and 0%, respectively.
- Key result
- Parameter:
- BOD5
- Value:
- 2 mg O2/g test mat.
- Remarks on result:
- other:
- Remarks:
- The test item was not readily biodegradable under the test conditions
- Results with reference substance:
- The percentage degradation of aniline after 7 days and 14 days were 73% and 85%, respectively.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- Under the conditions of the study, the average percentage biodegradation by BOD and that of the test item analytically were 2% and 0%, respectively. The test item was not readily biodegradable under the test conditions
- Executive summary:
The study evaluated the biodegradability of HES 10108 by microorganisms and the study was conducted according to OECD Guidelines 301C and Method for Testing the Biodegradability of Chemical Substances by Microrganisms stipulated in the Testing Methods for New Chemical Substances, Japan and in accordance with the Principles of GLP. The conditions of incubation were-
Concentration of test item - 100 mg/l
Concentration of activated sludge - 30 mg/l (as concentration of suspended solids)
Volume of test solution - 300 ml
Incubation temperature - 25 ± 1 °C
Incubation duration - 28 days (under dark condition)
Biodegradation was measured by estimating the BOD and analytically by measuring the concentration of the test item using validated HPLC methods.
Under the conditions of the study, the average percentage biodegradation by BOD and that of the test item analytically were 2% and 0%, respectively. The test item was not readily biodegradable under the test conditions
Reference
Description of key information
The study evaluated the biodegradability of HES 10108 by microorganisms and the study was conducted according to OECD Guidelines 301C and Method for Testing the Biodegradability of Chemical Substances by Microrganisms stipulated in the Testing Methods for New Chemical Substances, Japan and in accordance with the Principles of GLP. The conditions of incubation were-
Concentration of test item - 100 mg/l
Concentration of activated sludge - 30 mg/l (as concentration of suspended solids)
Volume of test solution - 300 ml
Incubation temperature - 25 ± 1 °C
Incubation duration - 28 days (under dark condition)
Biodegradation was measured by estimating the BOD and analytically by measuring the concentration of the test item using validated HPLC methods.
Under the conditions of the study, the average percentage biodegradation by BOD and that of the test item analytically were 2% and 0%, respectively. The test item was not readily biodegradable under the test conditions
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
- Type of water:
- other: activated sludge
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.