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EC number: 237-769-9 | CAS number: 13981-86-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17 September 2018 to 21 November 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- 2016
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- Version / remarks:
- 1998
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- column elution method
- Key result
- Water solubility:
- < 0.001 mg/L
- Conc. based on:
- element (dissolved fraction)
- Remarks:
- dissolved Niobium
- Temp.:
- 20 °C
- pH:
- >= 7.4 - <= 7.6
- Details on results:
- PRELIMINARY TEST
- The content of dissolved Niobium in the water samples was ≤ 0.00061 mg/L.
MAIN STUDY
- At a flow rate of 24 mL/h, the coefficient of variation (CV) (n = 10) was > 30 %. Therefore, sampling at this flow rate was repeated. The coefficient of variation (CV) (n = 10) was ≤ 30 % at 12 mL/h and at the repeat at 24 mL/h. It demonstrated that the system was equilibrated at these flow rates.
- At these flow rates, the analysed Niobium concentrations were far below that of the lowest calibration level. The analysed Niobium concentrations are therefore reported to be below that of the lowest calibration standard multiplied by the dilution factor (i.e. < 0.000728 mg/L).
- The turbidity of the eluates was < 0.2 NTU. According to this, no undissolved particles were detected in the eluates.
- Background response of Niobium was detected in the pre-treated samples from the blank column. These responses were comparable with the responses in the test samples. - Conclusions:
- Under the conditions of this study the water solubility of dissolved Niobium at 20 °C was < 0.000728 mg/L.
- Executive summary:
The water solubility of the test material was investigated in accordance with the standardised guidelines OECD 105, EU Method A6 and OPPTS 830.7840, under GLP conditions.
It proved not possible to dissolve the test material in nitric acid, nitric acid/hydrogen peroxide and hydrochloric acid. The test material dissolved in hydrofluoric acid but during removal of excess hydrofluoric acid using boric acid, the test material precipitated as a white solid.
For quantitative analysis, stock and calibration solutions with a known content are needed. As an alternative, an analytical standard of Niobium was purchased and used for analysis. As a result, concentrations measured are dissolved Niobium concentrations.
The column elution method was applied for the determination of the mass concentration of dissolved Niobium in water. The pH of the aqueous samples was 7.4 and 7.6.
Under the conditions of this study, the water solubility of dissolved Niobium at 20 °C was < 0.000728 mg/L.
Reference
Table 1: Main Study - Water Solubility of Dissolved Niobium
Flow Rate (mL/h) |
Sample No. |
Niobium Concentration Analysed |
pH |
||||
Individual1(mg/L) |
Mean2(mg/L) |
CV (%) |
Mean3(mg/L) |
MD (%) |
|||
244 |
1 |
0.00029 |
0.000716 |
1184 |
|
|
7.4 |
2 |
0.00028 |
||||||
3 |
0.00080 |
||||||
4 |
0.00025 |
||||||
5 |
0.00026 |
||||||
6 |
0.0026 |
||||||
7 |
0.00025 |
||||||
8 |
0.00025 |
||||||
9 |
0.0018 |
||||||
10 |
0.00028 |
||||||
12 |
1 |
0.000285 |
0.000227 |
12 |
0.000209 |
13 |
7.4 |
2 |
0.00165 |
||||||
3 |
0.000385 |
||||||
4 |
0.00022 |
||||||
5 |
0.00021 |
||||||
6 |
0.00027 |
||||||
7 |
0.00020 |
||||||
8 |
0.00021 |
||||||
9 |
0.00020 |
||||||
10 |
0.00021 |
||||||
24 |
1 |
0.00017 |
0.000198 |
23 |
|
|
7.6 |
2 |
0.00017 |
||||||
3 |
0.00030 |
||||||
4 |
0.00018 |
||||||
5 |
0.00017 |
||||||
6 |
0.00023 |
||||||
7 |
0.00018 |
||||||
8 |
0.00017 |
||||||
9 |
0.00016 |
||||||
10 |
0.00017 |
1: Obtained by extrapolation of the calibration curve.
2: Mean of the concentrations obtained at one flow rate.
3: Mean of the concentrations obtained at the flow rate of 12 mL/h and the repeated flow rate of 24 mL/h.
4: Coefficient of variation was >30 %, therefore sampling at this flowrate was repeated.
5: This value was not used for calculation of the mean because the system had not reached equilibrium yet.
6: The mean concentration obtained in the corresponding blank was 0.00020 mg/L.
7: A comparable mean concentration of 0.00020 mg/L was obtained in the corresponding blank.
8: A comparable mean concentration of 0.00017 mg/L was obtained in the corresponding blank.
9: The analysed concentrations were far below the lowest calibration level and are therefore reported to be below the lowest calibration standard, multiplied by the dilution factor (i.e. < 0.000728 mg/L).
Description of key information
Under the conditions of this study the water solubility of dissolved Niobium at 20 °C was < 0.000728 mg/L.
Key value for chemical safety assessment
- Water solubility:
- 0.001 mg/L
- at the temperature of:
- 20 °C
Additional information
The water solubility of the test material was investigated in accordance with the standardised guidelines OECD 105, EU Method A6 and OPPTS 830.7840, under GLP conditions. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).
It proved not possible to dissolve the test material in nitric acid, nitric acid/hydrogen peroxide and hydrochloric acid. The test material dissolved in hydrofluoric acid but during removal of excess hydrofluoric acid using boric acid, the test material precipitated as a white solid.
For quantitative analysis, stock and calibration solutions with a known content are needed. As an alternative, an analytical standard of Niobium was purchased and used for analysis. As a result, concentrations measured are dissolved Niobium concentrations.
The column elution method was applied for the determination of the mass concentration of dissolved Niobium in water. The pH of the aqueous samples was 7.4 and 7.6.
Under the conditions of this study, the water solubility of dissolved Niobium at 20 °C was < 0.000728 mg/L.
A value of 0.001 mg/L at 20 deg C is used for risk assessment purposes.
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