Reaction product aqueous Phosphoric Acid, 2-Butoxyethanol and 4,4'-Isopropylidenediphenol-Epichlorohydrin

Adsorption / desorption

Administrative data

Endpoint:

adsorption / desorption: screening

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance has a low octanol water partition coefficient and the adsorption potential of this substance is related to this parameter

Cross-reference

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

Endpoint:

partition coefficient

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.8 (Partition Coefficient - HPLC Method)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

HPLC method

Partition coefficient type:

octanol-water

Analytical method:

high-performance liquid chromatography

Type:

log Pow

Partition coefficient:

2.13

Temp.:

23 °C

pH:

6.077

Remarks on result:

other: Value is weighted average of constituent ranges.

Details on results:

Approximately 14 peaks were determined with peak areas ranging from 0.89 to 19.47%.

The Log Kow values of the test substance was:

72% of peaks have a Log Kow in the range < 0.3 to 2.03.

20% of peaks have a Log Kow in the range 2.98 to 4.49.

8% of peaks have a Log Kow in the range 4.69 to 6.21.

The weighted average Log Kow of the above values was 2.13. The majority of the peak areas had Log Kow values < 2.03.

Conclusions:

The substance is a UVCB and as such ranges of Log Kow values were provided. The weighted average of the Log Kow values of the various peaks was determined to be 2.13 at 23°C.