Registration Dossier
Registration Dossier
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EC number: 266-803-5 | CAS number: 67634-00-8
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vitro / ex vivo
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Remarks:
- QSAR
- Justification for type of information:
- QSAR The eye irritation QSAR prediction was assessed as adequate for regulatory purposes (Klimisch 2 – results derived from a valid QSAR model and falling into its applicability
domain, with adequate and reliable documentation /justification).
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- QSAR
- GLP compliance:
- no
Test material
- Reference substance name:
- Allyl (3-methylbutoxy)acetate
- EC Number:
- 266-803-5
- EC Name:
- Allyl (3-methylbutoxy)acetate
- Cas Number:
- 67634-00-8
- Molecular formula:
- C10H18O3
- IUPAC Name:
- allyl (3-methylbutoxy)acetate
- Test material form:
- liquid
Constituent 1
Results and discussion
In vitro
Results
- Irritation parameter:
- other: QSAR
- Remarks:
- QSAR
- Remarks on result:
- no indication of irritation
- Remarks:
- NOT EYE IRRITANT, based on probability of severe/moderate irritation equal to 0.31
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- NOT EYE IRRITANT, based on probability of severe/moderate irritation equal to 0.31
- Executive summary:
NOT EYE IRRITANT, based on probability of severe/moderate irritation equal to 0.31
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