Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
skin sensitisation, other
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1974
Report date:
1974

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: human_maximization_test
GLP compliance:
yes
Type of study:
other: human_maximization_test

Test material

Constituent 1
Chemical structure
Reference substance name:
2-cyclohexylethyl acetate
EC Number:
244-543-3
EC Name:
2-cyclohexylethyl acetate
Cas Number:
21722-83-8
Molecular formula:
C10H18O2
IUPAC Name:
2-cyclohexylethyl acetate

In vivo test system

Test animals

Species:
other: human
Strain:
other: human
Sex:
male

Results and discussion

In vivo (non-LLNA)

Results
Key result
Reading:
1st reading
Hours after challenge:
48
Group:
test chemical
No. with + reactions:
0
Total no. in group:
24
Clinical observations:
No evidence of contact sensitization was found in any of the preparations.
Remarks on result:
no indication of skin sensitisation

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
The test substance produced no reactions that were considered allergic in the 24 subjects tested.