Benzenesulfonic acid, C10-24-branched and linear alkyl derivs., magnesium salts, overbased

Partition coefficient

Administrative data

Endpoint:

partition coefficient

Type of information:

experimental study

Adequacy of study:

key study

Study period:

Experimental start date 22 November 2018 Experimental completion date 11 January 2019

Reliability:

1 (reliable without restriction)

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2019

Report date:

2019

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

EU Method A.8 (Partition Coefficient - HPLC Method)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)

Deviations:

no

GLP compliance:

yes

Type of method:

HPLC method

Partition coefficient type:

octanol-water

Test material

Test material information

Constituent 1

Reference substance name:

Benzenesulfonic acid, C10-24-branched and linear alkyl derivs., magnesium salts, overbased

EC Number:

948-935-1

Molecular formula:

Molecular formula cannot be determined for this UVCB substance

IUPAC Name:

Benzenesulfonic acid, C10-24-branched and linear alkyl derivs., magnesium salts, overbased

Test material form:

liquid: viscous

Details on test material:

Batch (Lot) Number: R18 14728
Expiry date: 08 October 2020 (expiry date)
Physical Description: Dark amber viscous liquid
Purity/Composition: UVCB
Storage Conditions: At room temperature

Specific details on test material used for the study:

Identity: T106D
Appearance: Viscous dark amber liquid
Batch number: R18 14728
Storage conditions: Room temperature (15 to 25°C)
Purity: UVCB 100%
Expiry date: 08 October 2020
Date received: 29 October 2018

Results and discussion

Partition coefficient

Key result

Type:

log Pow

Partition coefficient:

>= 4.3 - <= 7.2

Temp.:

25 °C

pH:

ca. 4

Any other information on results incl. tables

A calibration plot of log₁₀k’ versus log₁₀P_owwas constructed for the reference standards
(Table 1, Figure 1 - Please see Attachment 1 of this Summary). The logarithm of the capacity factor for the test item was then calculated and the log₁₀P_owvalues determined by interpolation.

The test item,T106D, chromatographed as a cluster of peaks between approximately 3.5 and 15 minutes and was determined to have log₁₀P_owvalues ranging from 4.3 to 7.2 (equivalent to a P_owrange of 21000 to 15000000), with a weight-averaged log₁₀P_owvalue of approximately 5.7 (Table 2 - Please see Attachment 2 of this Summary). Figures 2 to 4 present examples of chromatograms generated during this test (Please see these figures within Attachment 3 of this Summary).

Applicant's summary and conclusion

Conclusions:

T106D was determined to have log10Pow values ranging from 4.3 to 7.2 at 25°C, with a weight-averaged value of 5.7.

Executive summary:

The procedure outlined in this document has been designed to be compatible with the following guidelines and recommendations:

·          EC Method A.8

·          OECD Method 117

Conclusion

T106D was determined to have log₁₀P_owvalues ranging from 4.3 to 7.2 at 25°C, with a weight-averaged value of 5.7.