Registration Dossier
Registration Dossier
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EC number: 205-181-1 | CAS number: 135-16-0
Explosiveness
Administrative data
Link to relevant study record(s)
- Endpoint:
- explosive properties of explosives
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017-09-13 to 2018-01-31
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- UN Manual of Tests and Criteria: Part I: Classification procedures, test methods and criteria relating to explosives of Class 1
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Key result
- Parameter:
- other: exothermic decomposition
- Remarks on result:
- other: no exothermic decomposition was detected up to 500°C
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- In the DSC-measurement no exothermic decomposition of the test item Tetrahydrofolic acid could be observed up to a temperature of 500 °C. Therefore, further tests for explosive properties did not have to be performed.
According to the results of the test on thermal stability, the test item is classified as follows:
UN Transport Regulation: The test item does not have to be classified as explosive substance in class 1 according to the UN Transport Regulation.
GHS (CLP Regulation EC 1272/2008: Annex 1: 2.1): The test item does not have to be classified as explosive substance according to GHS or CLP Regulation EC 1272/2008 Annex 1: 2.1, respectively.
Reference
Description of key information
Explosiveness: non explosive (UN Manual of Tests and Criteria: Part I, GLP)
Key value for chemical safety assessment
- Explosiveness:
- non explosive
Additional information
In the DSC-measurement no exothermic decomposition of the test itemTetrahydrofolic acid could be observed up to a temperature of 500 °C. Therefore, further tests for explosive properties did not have to be performed.
Justification for classification or non-classification
Based on the available data, tetrahydrofolic acid does not meet the classification criteria for explosive solids according to Regulation (EC) No. 1272/2008 (CLP) and the Globally Harmonized System of Classification of Chemicals (GHS).
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