Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 485-430-0 | CAS number: 923954-49-8
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Acutely harmful to algae
Key value for chemical safety assessment
- EC10 or NOEC for freshwater algae:
- 10 mg/L
Additional information
An acute GLP test on green algae Pseudokirchneriella subcapitata according to OECD guideline 201 was identified as key study (BASF 2008). As the test substance is poorly soluble in water an eluate of three different loading concentrations was tested according to OECD 29. After 72 hours of exposure an EL50 between 10 -100 mg/L was evaluated, the NOEC was estimated to be 10 mg/L, both related to the nominal loading rate.
In a supporting study with Pseudokirchneriella subcapitata ECx and NOEC values based on growth rate and yield were determined. In some of the freshly prepared and in some of the aged exposure solutions the concentration of the test item deviated with more than 20 % of the nominal loading rate, thus, all biological endpoints were based on the mean measured concentrations. The EC10 and EC50 based on growth rate were determined to be 5.64 mg/L and 39.3 mg/L, respectively. The EC10 and EC50 based on yield were determined to be 1.90 mg/L and 8.94 mg/L, respectively. The NOEC for growth rate was 7.98 mg/L and for yield - 3.86 mg/L, respectively.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
