Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-749-9 | CAS number: 149-91-7
Appearance / physical state / colour
Administrative data
Link to relevant study record(s)
- Endpoint:
- appearance / physical state / colour
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Principles of method if other than guideline:
- Observation
- GLP compliance:
- no
- Specific details on test material used for the study:
- Gallic acid was obtained from Dainippon Pharmaceutical Co. Ltd (Osaka, Japan), as a yellowish-white crystalline powder with a purity over 98%. The preparation had little odor, and was astringent and somewhat acid in taste.
- Physical state at 20°C and 1013 hPa:
- solid
- Remarks:
- yellowish-white crystalline powder
- Conclusions:
- Gallic acid with a purity of 98% is described as a yellowish-white crystalline powder in 90-day subchronic toxicity on rats.
- Executive summary:
Gallic acid with a purity of 98% is described as a yellowish-white crystalline powder in 90-day subchronic toxicity on rats.
- Endpoint:
- appearance / physical state / colour
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Principles of method if other than guideline:
- Observation
- GLP compliance:
- no
- Specific details on test material used for the study:
- 3,4,5-trihydroxybenzoic acid (gallic acid hydrate; CAS# 149-91-7; Lot# CBEJB; mass fraction purity ≥ 0.97 powder) was obtained from VWR (Batavia, IL, USA)
- Physical state at 20°C and 1013 hPa:
- solid
- Remarks:
- powder
- Conclusions:
- Gallic acid with a purity ≥ 97% is described as a powder in water solubility test.
- Executive summary:
Gallic acid with a purity ? 97% is described as a powder in water solubility test.
- Endpoint:
- appearance / physical state / colour
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Principles of method if other than guideline:
- observation
- GLP compliance:
- no
- Specific details on test material used for the study:
- Gallic acid (98 % purity) was obtained as dry powder from Acros Organics (no. 410860010).
- Physical state at 20°C and 1013 hPa:
- solid
- Remarks:
- dry powder
- Conclusions:
- Gallic acid witha purity of 98% is described as a dry powder in fish acute toxicity test.
- Executive summary:
Gallic acid witha purity of 98% is described as a dry powder in fish acute toxicity test.
- Endpoint:
- appearance / physical state / colour
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: no guideline applies to this simple observation endpoint
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- visual inspection
- GLP compliance:
- no
- Physical state at 20°C and 1013 hPa:
- solid
- Key result
- Form:
- solid
- Colour:
- white or yellowish-white or fawn-colored, crystalline needles or prisms
- Odour:
- odourless
- Substance type:
- organic
- Conclusions:
- The test item is a white or yellowish-white or fawn-colored solid, in the form of crystalline needles or prisms, odorless.
Referenceopen allclose all
Description of key information
The weight of evidence approach may apply as 3 independent sources of information are availble.
The state of gallic acid (with purity between 97 and 98%) is provided as information in material and methods of three publications:
-Yellowish-white crystalline powder in 90 -day subchronic toxicity test on rats (Niho et al., 2001)
- Dry powder in fish acute toxicity test (Techer et al., 2015a)
- Powder in water solubility test (Srinivas et al., 2010)
This is supported by visual inspection of the test item that is is a white or yellowish-white or fawn-colored solid, in the form of crystalline needles or prisms, odorless.
Key value for chemical safety assessment
- Physical state at 20°C and 1013 hPa:
- solid
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
