Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 290-505-4 | CAS number: 90170-70-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- March 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- > 6.5
- Temp.:
- 25 °C
- Remarks on result:
- other: Results for 3 main components
- Type:
- log Pow
- Partition coefficient:
- > 1.38 - < 6.5
- Temp.:
- 25 °C
- Remarks on result:
- other: Values reported for other peaks, but not the main components: impurities
- Details on results:
- The chromatogram showed a total of 13 peaks and the log Pow was calculated for all of them. However the 3 main peaks, being the largest in size and also the latest eluting which represent the 3 main components of this multiconstituent material all had a calculated log Pow of >6.5. This is also consistent with QSAR predictions using the Episuite KOWWIN software which predicts values ranging from 11 - 11.4 for the 3 main components.
- Conclusions:
- The partition coefficient (log Pow) of Solvent Blue 79B was estimated using high performance liquid chromatography.
The test item showed 13 visible peaks, estimated log Pow of: 1.38 ± 0.09 to > 6.5 (with 95 % confidence interval). The 3 main components of this mutliconstituent material all have a log Pow of >6.5 and it is this value that will be used for the CSR. - Executive summary:
The partition coefficient (log Pow) of Solvent Blue 79B was estimated using high performance liquid chromatography in accordance with OECD method 117.
The test item showed 13 visible peaks and the log Pow was calculated for all of them.
This gave estimated log Pow of: 1.38 ± 0.09 to > 6.5 (with 95 % confidence interval). The 3 main components of this
However the 3 main peaks, being the largest in size and also the latest eluting which represent the 3 main components of this multiconstituent material all had a calculated log Pow of >6.5. This is also consistent with QSAR predictions using the Episuite KOWWIN software which predicts values ranging from 11 - 11.4 for the 3 main components. A value of >6.5 will be used for the CSR.
Reference
Table 1.: Measured and calculated data of the reference substances
Chemical name |
log Pow |
Retention time (min) |
log k |
Repeatability |
Reproducibility |
log Pow |
OECD 117 |
Calculated |
Calculated |
||||
Thiourea |
- |
2.37 |
for determination of dead time |
|||
2.38 |
||||||
2.37 |
||||||
2.37 |
||||||
2.37 |
||||||
2.38 |
||||||
Mean |
2.37 |
|||||
CV% |
0.2 |
|||||
Benzonitrile |
1.6 |
3.28 |
-0.418 |
0.04 |
0.2 |
1.4 |
3.28 |
-0.418 |
1.4 |
||||
3.29 |
-0.413 |
1.4 |
||||
3.29 |
-0.413 |
1.4 |
||||
3.29 |
-0.413 |
1.4 |
||||
3.30 |
-0.408 |
1.4 |
||||
Mean |
3.29 |
-0.414 |
1.4 |
|||
CV% |
0.2 |
- |
- |
|||
Methyl benzoate |
2.1 |
3.75 |
-0.237 |
0.03 |
0.1 |
2.2 |
3.74 |
-0.240 |
2.2 |
||||
3.74 |
-0.240 |
2.2 |
||||
3.74 |
-0.240 |
2.2 |
||||
3.74 |
-0.240 |
2.2 |
||||
3.73 |
-0.243 |
2.2 |
||||
Mean |
3.74 |
-0.240 |
2.2 |
|||
CV% |
0.2 |
- |
- |
|||
Ethyl benzoate |
2.6 |
4.29 |
-0.093 |
0.01 |
0.2 |
2.8 |
4.30 |
-0.091 |
2.9 |
||||
4.29 |
-0.093 |
2.8 |
||||
4.29 |
-0.093 |
2.8 |
||||
4.29 |
-0.093 |
2.8 |
||||
4.29 |
-0.093 |
2.8 |
||||
Mean |
4.29 |
-0.092 |
2.8 |
|||
CV% |
0.1 |
- |
- |
|||
Benzophenone |
3.2 |
4.46 |
-0.056 |
0.01 |
0.2 |
3.0 |
4.46 |
-0.056 |
3.0 |
||||
4.45 |
-0.058 |
3.0 |
||||
4.46 |
-0.056 |
3.0 |
||||
4.46 |
-0.056 |
3.0 |
||||
4.46 |
-0.056 |
3.0 |
||||
Mean |
4.46 |
-0.056 |
3.0 |
|||
CV% |
0.1 |
- |
- |
Table 2: Measured and calculated data of test item
|
Retention time (min) |
log k |
log Pow |
Pow |
Calculated data |
||||
Solvent Blue 79B peak 1 |
3.27 |
-0.423 |
1.38 |
23.9 |
3.27 |
-0.423 |
1.38 |
23.9 |
|
3.27 |
-0.423 |
1.38 |
23.9 |
|
3.27 |
-0.423 |
1.38 |
23.9 |
|
3.28 |
-0.418 |
1.40 |
25.1 |
|
3.27 |
-0.423 |
1.38 |
23.9 |
|
Mean |
3.27 |
-0.422 |
1.38 |
24.1 |
Conf.(95%) |
- |
- |
0.009 |
- |
CV% |
0.1 |
- |
- |
- |
Solvent Blue 79B peak 2 |
4.33 |
-0.084 |
2.88 |
765 |
4.33 |
-0.084 |
2.88 |
765 |
|
4.32 |
-0.086 |
2.87 |
748 |
|
4.32 |
-0.086 |
2.87 |
748 |
|
4.33 |
-0.084 |
2.88 |
765 |
|
4.33 |
-0.084 |
2.88 |
765 |
|
Mean |
4.33 |
-0.085 |
2.88 |
759 |
Conf.(95%) |
- |
- |
0.005 |
- |
CV% |
0.1 |
- |
- |
- |
Solvent Blue 79B peak 3 |
5.32 |
0.094 |
3.67 |
4712 |
5.31 |
0.092 |
3.67 |
4642 |
|
5.32 |
0.094 |
3.67 |
4712 |
|
5.32 |
0.094 |
3.67 |
4712 |
|
5.32 |
0.094 |
3.67 |
4712 |
|
5.32 |
0.094 |
3.67 |
4712 |
|
Mean |
5.32 |
0.094 |
3.67 |
4700 |
Conf.(95%) |
- |
- |
0.003 |
- |
CV% |
0.1 |
- |
- |
- |
Solvent Blue 79B peak 4 |
6.77 |
0.268 |
4.45 |
27864 |
6.77 |
0.268 |
4.45 |
27864 |
|
6.76 |
0.267 |
4.44 |
27584 |
|
6.77 |
0.268 |
4.45 |
27864 |
|
6.77 |
0.268 |
4.45 |
27864 |
|
6.78 |
0.269 |
4.45 |
28174 |
|
Mean |
6.77 |
0.268 |
4.45 |
|
Conf.(95%) |
- |
- |
0.003 |
- |
CV% |
0.1 |
- |
- |
- |
Solvent Blue 79B peak 5 |
13.05 |
0.653 |
6.16 |
1433014 |
13.05 |
0.653 |
6.16 |
1433014 |
|
13.03 |
0.652 |
6.15 |
1421131 |
|
13.05 |
0.653 |
6.16 |
1433014 |
|
13.04 |
0.653 |
6.15 |
1427063 |
|
13.05 |
0.653 |
6.16 |
1433014 |
|
Mean |
13.05 |
0.653 |
6.16 |
1430041 |
Conf.(95%) |
- |
- |
0.002 |
- |
CV% |
0.1 |
- |
- |
- |
Solvent Blue 79B peak 6 |
17.47 |
- |
- |
- |
17.48 |
- |
- |
- |
|
17.47 |
- |
- |
- |
|
17.48 |
- |
- |
- |
|
17.46 |
- |
- |
- |
|
17.48 |
- |
- |
- |
|
Mean |
17.47 |
- |
- |
- |
Conf.(95%) |
- |
- |
> 6.5 |
- |
CV% |
0.1 |
- |
- |
- |
Solvent Blue 79B peak 7 |
18.97 |
- |
- |
- |
18.91 |
- |
- |
- |
|
18.90 |
- |
- |
- |
|
18.94 |
- |
- |
- |
|
18.93 |
- |
- |
- |
|
18.95 |
- |
- |
- |
|
Mean |
18.93 |
- |
- |
- |
Conf.(95%) |
- |
- |
> 6.5 |
- |
CV% |
0.1 |
- |
- |
- |
Solvent Blue 79B peak 8 |
22.40 |
- |
- |
- |
22.41 |
- |
- |
- |
|
22.40 |
- |
- |
- |
|
22.41 |
- |
- |
- |
|
22.40 |
- |
- |
- |
|
22.41 |
- |
- |
- |
|
Mean |
22.41 |
- |
- |
- |
Conf.(95%) |
- |
- |
> 6.5 |
- |
CV% |
0.0 |
- |
- |
- |
Solvent Blue 79B peak 9 |
24.73 |
- |
- |
- |
24.74 |
- |
- |
- |
|
24.72 |
- |
- |
- |
|
24.73 |
- |
- |
- |
|
24.71 |
- |
- |
- |
|
24.75 |
- |
- |
- |
|
Mean |
24.73 |
- |
- |
- |
Conf.(95%) |
- |
- |
> 6.5 |
- |
CV% |
0.1 |
- |
- |
- |
Solvent Blue 79B peak 10 |
26.89 |
- |
- |
- |
26.84 |
- |
- |
- |
|
26.87 |
- |
- |
- |
|
26.87 |
- |
- |
- |
|
26.88 |
- |
- |
- |
|
26.90 |
- |
- |
- |
|
Mean |
26.88 |
- |
- |
- |
Conf.(95%) |
- |
- |
> 6.5 |
- |
CV% |
0.1 |
- |
- |
- |
Solvent Blue 79B peak 11 |
35.07 |
- |
- |
- |
35.08 |
- |
- |
- |
|
35.06 |
- |
- |
- |
|
35.07 |
- |
- |
- |
|
35.05 |
- |
- |
- |
|
35.08 |
- |
- |
- |
|
Mean |
35.07 |
- |
- |
- |
Conf.(95%) |
- |
- |
> 6.5 |
- |
CV% |
0.0 |
- |
- |
- |
Solvent Blue 79B peak 12 |
36.63 |
- |
- |
- |
36.65 |
- |
- |
- |
|
36.63 |
- |
- |
- |
|
36.63 |
- |
- |
- |
|
36.62 |
- |
- |
- |
|
36.67 |
- |
- |
- |
|
Mean |
36.64 |
- |
- |
- |
Conf.(95%) |
- |
- |
> 6.5 |
- |
CV% |
0.1 |
- |
- |
- |
Solvent Blue 79B peak 13 |
52.37 |
- |
- |
- |
52.38 |
- |
- |
- |
|
52.36 |
- |
- |
- |
|
52.36 |
- |
- |
- |
|
52.37 |
- |
- |
- |
|
52.40 |
- |
- |
- |
|
Mean |
52.37 |
- |
- |
- |
Conf.(95%) |
- |
- |
> 6.5 |
- |
CV% |
0.0 |
- |
- |
- |
Description of key information
The partition coefficient (log Pow) of Solvent Blue 79B was estimated using high performance liquid chromatography according to method OECD 117.
The test item showed 13 visible peaks the log Pow of which ranged from 1.38 ± 0.09 to > 6.5
The 3 main components of this mutliconstituent material all have a log Pow of >6.5 and it is this value that will be used for the CSR.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 6.5
- at the temperature of:
- 25 °C
Additional information
The partition coefficient (log Pow) of Solvent Blue 79B was estimated using high performance liquid chromatography in accordance with OECD method 117.
The test item showed 13 visible peaks and the log Pow was calculated for all of them.
This gave estimated log Pow of: 1.38 ± 0.09 to > 6.5 (with 95 % confidence interval). The 3 main components of this
However the 3 main peaks, being the largest in size and also the latest eluting which represent the 3 main components of this multiconstituent material all had a calculated log Pow of >6.5. This is also consistent with QSAR predictions using the Episuite KOWWIN software which predicts values ranging from 11 - 11.4 for the 3 main components. A value of >6.5 will be used for the CSR.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.