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EC number: 271-663-3 | CAS number: 68603-55-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- not specified
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- yes
- Vehicle:
- no
- Details on test solutions:
- The test item was tested for toxicity towards daphnia as aqueous extracts ("WAF") from up to 100 mg test item/L (final concentration).
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Daphnia magna STRAUS (clone 5) of Iabaratory bred (derived from Dr. M. Bergtold, BASF, D-67117 Limburgerhof; the strain originally derived from the Institut National de Recherche Chimique Appliquee, France in 1978 and cultivated since then at BASF using medium M4 acc. Elendt) were used for the test. ln order to verify the sensitivity of the test system towards toxic items the effect of potassium dichromate towards different animals of this bred was tested prior to beginning of the test. The value of the EC50 (24h) in this period of time was 1.13 mg/L potassium dichromate. This value is in accordance with the recommendations given in OECD Guideline 202 (Daphnia sp., Acute Immobilisation Test). The cultivation of the daphnia is performed in a way that the animals are transferred in new test medium (see below) at an interval of 1 to 3 days followed by feeding with Desmodesmus subspicatus- and/or Chlorella-cells. Daphnia used for the test are not older than 24h. Therefore, in every case, daphnia are transferred into fresh medium one day before starting of the daphnia test in order to get daphnia for the test younger than 24h. During the test the daphnia were not fed.
- Test type:
- not specified
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
- Test temperature:
- ca 21 °C
- pH:
- ca 8.5
- Dissolved oxygen:
- 5.9 - 8.6 mg O2/L
- Reference substance (positive control):
- yes
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- ca. 0.315 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- other: "WAF", water accommodated fraction
- Basis for effect:
- mobility
- Key result
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- ca. 0.2 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- other: "WAF", water accommodated fraction
- Basis for effect:
- mobility
- Validity criteria fulfilled:
- yes
- Conclusions:
- "DEOPHOS 228" was tested for acute toxicity towards Daphnia according to OECD-Test Guideline 202. ln order to investigate the influence of the test item towards the daphnia, the swimming behaviour of the animals was recorded. Under the conditions used for the test, immobilisation of the daphnia was observed at concentrations representing the water soluble part (hereafter abbreviated "WAF", water accommodated fraction) of the test item of ~0.1 mg/L. The following EL-values (effective loading rate) are assumed according to the results of this test:
t24h t48h
NOEC No precise value is given by the system 0.20 mg/L
LOEC No value given by the system 0.40 mg/L
EL1o 0.284 mg/L (0.222 - 0.364) 0.261 mg/L (no Iimits given)
EL2o 0.334 mg/L (0.272 - 0.411) 0.278 mg/L (no Iimits given)
EL5o 0.456 mg/L (0.389- 0.535) 0.315 mg/L (no Iimits given)
Values in brackets indicate the 95% confidence Iimits. The test results are based on the nominal concentrations being tested as the test item was measured to be stable at in the aqueous phase at ~80% during incubation. The criteria of validity of results given by the OECD-Test Guideline 202 (version dated 13-Apr-2004) were kept within this study:
• ln the control without any test item no dead animals were observed.
• ln the test solutions the oxygen Goncentration did not drop below a value of 60% of the saturation
value ("' 5 mg 02/L). - Executive summary:
The test substance was tested for acute toxicity towards Daphnia according to OECD-Test Guideline 202. ln order to investigate the influence of the test item towards the daphnia, the swimming behaviour of the animals was recorded. Under the conditions used for the test, immobilisation of the daphnia was observed at concentrations representing the water soluble part (hereafter abbreviated "WAF", water accommodated fraction) of the test item of ~0.1 mg/L. The following EL-values (effective loading rate) are assumed according to the results of this test:
t24h t48h
NOEC No precise value is given by the system 0.20 mg/L
LOEC No value given by the system 0.40 mg/L
EL1o 0.284 mg/L (0.222 - 0.364) 0.261 mg/L (no Iimits given)
EL2o 0.334 mg/L (0.272 - 0.411) 0.278 mg/L (no Iimits given)
EL5o 0.456 mg/L (0.389- 0.535) 0.315 mg/L (no Iimits given)
Values in brackets indicate the 95% confidence Iimits. The test results are based on the nominal concentrations being tested as the test item was measured to be stable in the aqueous phase at ~80% during incubation.
Reference
10-1.2 Main Test Loading of the test item (mg/L) (Eluates/"WAF") |
Ratio immobilised Daphnia [0/0] 24 h 48h |
pH-Value to 48h |
02-Content [mg 02/L] to 48h |
Temperature to 48h |
||||
Control (0) 0.1 0.2 0.4 0.8 1 .0 |
o [0/20]1)o [0/20]1)o [0/20]1) 40 [8/20]1) 90 [1 8/20]1) 100 [20/20]1) |
5 [1/20]1)o [0/20]1) 5 [1/20]1) 95 [1 9/20]1) 100 [20/20]1) 100 [20/2011) |
8.51 8.48 8.49 8.47 8.57 8.59 |
8.54 8.25 8.41 8.35 8.33 8.53 |
8.6 6.2 5.9 6.1 5.7 6.1 |
8.3 7.7 7.1 7.3 6.0 6.5 |
21 .0 21 .0 21 .0 21.o 21.0 21.o |
19.9 20.0 20.0 20.0 20.1 20.2 |
1) Numbers in brackets give the absolute numbers of immobilised animals at each concentration.
Description of key information
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.315 mg/L
Additional information
The test substance was tested for acute toxicity towards Daphnia according to OECD-Test Guideline 202. ln order to investigate the influence of the test item towards the daphnia, the swimming behaviour of the animals was recorded. Under the conditions used for the test, immobilisation of the daphnia was observed at concentrations representing the water soluble part (hereafter abbreviated "WAF", water accommodated fraction) of the test item of ~0.1 mg/L. The following EL-values (effective loading rate) are assumed according to the results of this test:
t24h t48h
NOEC No precise value is given by the system 0.20 mg/L
LOEC No value given by the system 0.40 mg/L
EL1o 0.284 mg/L (0.222 - 0.364) 0.261 mg/L (no Iimits given)
EL2o 0.334 mg/L (0.272 - 0.411) 0.278 mg/L (no Iimits given)
EL5o 0.456 mg/L (0.389- 0.535) 0.315 mg/L (no Iimits given)
Values in brackets indicate the 95% confidence Iimits. The test results are based on the nominal concentrations being tested as the test item was measured to be stable in the aqueous phase at ~80% during incubation.
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