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Diss Factsheets
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EC number: 947-623-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Due to the differences in the physicochemical characteristics of the components of the reaction mass of 2,4,6 -tris(1 -phenylethyl)phenol and Bis(1 -phenylethyl)phenol, any distyrenated phenol and tristyrenated phenol released to the environment will not behave as a single compound. Significant variation is expected in the environmental fate and behaviour of these compounds. As a consequence, it was considered more appropriate to conduct this assessment for each component, that is to say for Tristyrenated phenol (TSP) and Distyrenated phenol (DSP).
One reliable key study on the hydrolysis potential of DSP is available (Lange, 2006). DSP was found to be hydrotically stable in the four test conditions: buffer solution at pH 7 saturated with nitrogen, algal test medium (according to OECD TG 201) saturated with nitrogen, buffer solution at pH 7 saturated with oxygen and algal test medium (according to OECD TG 201) saturated with oxygen. As TSP contains the same functional groups as DSP, TSP is not expected to have a higher hydrolysis potential than DSP. Moreover, this assumption is supported by the steric hindrance caused by the additional styrene group substituted on the phenol ring of TSP. Therefore, it is considered that TSP is hydrotically stable in similar conditions as DSP.
One reliable key study (BAZZON, 1997) is available for the assessment of the ready biodegradability.The test substance (80% TSP and 20% DSP) was found to be not readily biodegradable with pre-adapted inoculum. As no biodegradation was observed during the test, it is proposed to apply this conclusion to both components DSP and TSP.
This was further confirmedd by way of the Catalogic QSAR. The model prediction indicates that the individual constituents TSP, 2,6-DSP and 2,4-DSP are not ready biodegradable.
The Catalog model does predict a number of soil degradation pathways for TSP, 2,6-DSP and 2,4-DSP. The predicted biodegradation in soil is supported by documented metabolism for an analogue chemical. The model however does not provide a soil degradation half-life.
Based on the measured logKow values above 6, DSP and TSP may have a potential of bioaccumulation. One reliable key dietary bioaccumulation study (Lange, 2006) is available on a mixture of TSP / DSP (60% / 40%). This study showed that DSP is not bioaccumulable. For TSP, the study determined a BMF < 1, therefore, it has a low potential for biomagnification.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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