Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2016-01-20 to 2016-01-22
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- static method
- Key result
- Test no.:
- #1
- Temp.:
- 20 °C
- Vapour pressure:
- 455 Pa
- Key result
- Test no.:
- #1
- Temp.:
- 25 °C
- Vapour pressure:
- 559 Pa
- Conclusions:
- Vapour pressure values of 455 Pa at 20°C and 559 Pa at 25°C were obtained for the substance using a relevant test method and in compliance with GLP. The result is considered to be reliable.
Reference
The results of the static vapour pressure experiment are presented in Table 1 and Table 2 below, the summarised results are in Table 3.
Table 1: Determination of the vapour pressure of the test substance during the static vapour pressure experiment - Replicate 1
Test Temperature (°C) |
Test Temperature (K) |
Test temperature (1/K) |
Vapour pressure (Pa) |
ln Vapour pressure (Pa) |
-10.2 |
262.95 262.95 262.95 |
0.00380 0.00380 0.00380 |
98.3 99.3 100 |
4.59 4.60 4.61 |
Mean (Standard deviation) |
99.2 (0.854) |
4.60 (0.00862) |
||
-5.1 |
268.05 268.05 268.05 |
0.00373 0.00373 0.00373 |
145 148 153 |
4.98 5.00 5.03 |
Mean (Standard deviation) |
149 (4.04) |
5.00 (0.0271) |
||
0.40 |
273.55 273.55 273.55 |
0.00366 0.00366 0.00366 |
190 193 197 |
5.25 5.26 5.28 |
Mean (Standard deviation) |
193 (3.51) |
5.23 (0.0181) |
||
6.8 |
279.95 279.95 279.95 |
0.00357 0.00357 0.00357 |
235 238 241 |
5.46 5.47 5.47 |
Mean (Standard deviation) |
238 (3.00) |
5.47 (0.0126) |
||
12.1 |
285.25 285.25 285.25 |
0.00351 0.00351 0.00351 |
313 316 319 |
5.75 5.76 5.77 |
Mean (Standard deviation) |
316 (3.00) |
5.76 (0.00949) |
||
-9.0 |
264.15 264.15 264.15 |
0.00379 0.00379 0.00379 |
127 128 129 |
4.84 4.85 4.86 |
Mean (Standard deviation) |
128 (1.00) |
4.85 (0.00781) |
Table 2: Determination of the vapour pressure of the test substance during the static vapour pressure experiment - Replicate 2
Test Temperature (°C) |
Test Temperature (K) |
Test temperature (1/K) |
Vapour pressure (Pa) |
ln Vapour pressure (Pa) |
9.8 |
282.95 282.95 282.95 |
0.00353 0.00353 0.00353 |
279 286 288 |
5.63 5.66 5.66 |
Mean (Standard deviation) |
284 (4.73) |
5.65 (0.0167) |
||
15.0 |
288.15 288.15 288.15 |
0.00347 0.00347 0.00347 |
362 362 362 |
5.89 5.89 5.89 |
Mean (Standard deviation) |
362 (0.00) |
5.89 (0.00) |
||
20.0 |
293.15 293.15 293.15 |
0.00341 0.00341 0.00341 |
458 461 461 |
6.13 6.13 6.13 |
Mean (Standard deviation) |
460 (1.73) |
6.13 (0.00377) |
||
25.3 |
298.45 298.45 298.45 |
0.00335 0.00335 0.00335 |
559 557 559 |
6.33 6.32 6.33 |
Mean (Standard deviation) |
558 (1.15) |
6.32 (0.00207) |
||
30.1 |
303.25 303.25 303.25 |
0.00330 0.00330 0.00330 |
678 682 683 |
6.52 6.53 6.53 |
Mean (Standard deviation) |
681 (2.65) |
6.52 (0.00389) |
||
9.8 |
282.95 282.95 282.95 282.95 |
0.00353 0.00353 0.00353 0.00353 |
339 316 317 317 |
5.83 5.76 5.76 5.76 |
Mean (Standard deviation) |
322 (11.2) |
5.77 (0.0341) |
Note: Numbers may vary slightly due to rounding. Table includes all values to show stability over all measurements.
Table 3: Summary of results
Replicate |
Test Temperature (°C) |
Test Temperature (K) |
Test temperature (1/K) |
Vapour pressure (Pa) |
ln Vapour pressure (Pa) |
1 |
-10.2 |
262.95 |
3.80E-03 |
99.2 |
4.60E+00 |
1 |
-5.1 |
268.05 |
3.73E-03 |
149 |
5.00E+00 |
1 |
0.40 |
273.55 |
3.66E-03 |
193 |
5.26E+00 |
1 |
6.8 |
279.55 |
3.57E-03 |
238 |
5.47E+00 |
1 |
12.1 |
285.25 |
3.51E-03 |
316 |
5.76E+00 |
1 |
-9.0 |
264.15 |
3.79E-03 |
128 |
4.85E+00 |
2 |
9.8 |
282.95 |
3.53E-03 |
284 |
5.65E+00 |
2 |
15.0 |
288.15 |
3.47E-03 |
362 |
5.89E+00 |
2 |
20.0 |
293.15 |
3.41E-03 |
460 |
6.13E+00 |
2 |
25.3 |
298.45 |
3.35E-03 |
558 |
6.32E+00 |
2 |
30.1 |
303.25 |
3.30E-03 |
681 |
6.52E+00 |
2 |
9.8 |
282.95 |
3.53E-03 |
322 |
5.77E+00 |
When the data from both experiments are plotted together using the Clausious Clapeyon equation and linear regression is performed; the vapour pressure is extrapolated to be 455 Pa at 20°C and 559 Pa at 25°C. These estimates are confirmed by the observations of vapour pressure values of 460 Pa at 20°C and 558 Pa at 25.3°C during the definitive experiments.
Description of key information
Vapour Pressure [ Reaction mass of 3-(2,3-epoxypropoxy)propyltrimethoxysilane and triacetoxyvinylsilane]: 455 Pa at 20°C (OECD 104)
Vapour Pressure [3-(2,3-epoxypropoxy)propyl]silanetriol]: 1.7E-05 Pa at 25°C (QSAR)
Vapour Pressure [Vinylsilanetriol]: 1.7E-02 Pa at 25°C (QSAR)
Vapour Pressure [acetic acid]: 2090 Pa at 25°C
Vapour Pressure [methanol]: 12790 Pa at 20°C
Key value for chemical safety assessment
- Vapour pressure:
- 455 Pa
- at the temperature of:
- 20 °C
Additional information
Vapour pressure values of 455 Pa at 20°C and 559 Pa at 25°C were determined for the substance using a static method in accordance with OECD Test Guideline 104 and in compliance with GLP. The result is considered to be reliable.
In contact with water, the substance hydrolyses rapidly (all constituents have predicted half-lives of <12 hours at 20- 25°C and pH 4, pH 7 and pH 9) to form 3-(2,3-epoxypropoxy)propyl]silanetriol, vinylsilanetriol, acetic acid and methanol. The vapour pressure of the silanol hydrolysis products, 3-(2,3-epoxypropoxy)propyl]silanetriol and vinylsilanetriol have been predicted to be 1.7E-05 Pa and 1.7E-02 at 25°C respectively using a validated QSAR estimation method.
A vapour pressure of 2090 Pa at 25°C was reported for acetic acid (Daubert and Danner 1985).
Methanol has a reported vapour pressure of 12790 Pa at 20°C (OECD 2004).
References:
Daubert and Danner (1985). Data compilation tables of properties of pure compounds. American Institute of Chemical Engineers. pp.450, 1985.
OECD 2004. SIDS Initial Assessment Report for SIAM 19, Berlin, Germany, 18-20 October 2004, Methanol, CAS 67-56-1
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.