Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-353-5 | CAS number: 81-48-1
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Remarks:
- The conduction of an acute inhalation toxicity study was not possible, because the properties of Macrolex Violett B were unfavorable to produce a suitable test atmosphere.
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 016
- Report date:
- 2016
Materials and methods
- Principles of method if other than guideline:
- A study was performed to assess the acute inhalation toxicity of the test item. The method used was designed to be compatible with that described in the OECD Guideline for Testing of Chemicals (2009) No. 436 "Acute Inhalation Toxicity- Acute Toxic Class Method" and Method B.52. Acute Inhalation Toxicity-Acute Toxic Class Method, 2014, of Commission Regulation (EC) No. 440/2008.
The properties of Macrolex Violett B were shown to be unfavorable to produce a suitable test atmosphere. Mechanical systems designed to produce dust aerosols were unsuccessful in producing a suitable test atmosphere with a particle size that would have been in full compliance with the inhalation test guidelines. It was, therefore, considered to be not possible to generate a suitable test atmosphere from the test item, for use in an inhalation study.
Test material
- Reference substance name:
- 1-hydroxy-4-(p-toluidino)anthraquinone
- EC Number:
- 201-353-5
- EC Name:
- 1-hydroxy-4-(p-toluidino)anthraquinone
- Cas Number:
- 81-48-1
- Molecular formula:
- C21H15NO3
- IUPAC Name:
- 1-hydroxy-4-[(4-methylphenyl)amino]-9,10-anthraquinone
Constituent 1
Results and discussion
Applicant's summary and conclusion
- Executive summary:
A study was performed to assess the acute inhalation toxicity of the test item. The method used was designed to be compatible with that described in the OECD Guideline for Testing of Chemicals (2009) No. 436 "Acute Inhalation Toxicity- Acute Toxic Class Method" and Method B.52. Acute Inhalation Toxicity-Acute Toxic Class Method, 2014, of Commission Regulation (EC) No. 440/2008.
The properties of Macrolex Violett B were shown to be unfavorable to produce a suitable test atmosphere. Mechanical systems designed to produce dust aerosols were unsuccessful in producing a suitable test atmosphere with a particle size that would have been in full compliance with the inhalation test guidelines. It was, therefore, considered to be not possible to generate a suitable test atmosphere from the test item, for use in an inhalation study.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
