Registration Dossier
Registration Dossier
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EC number: 208-686-5 | CAS number: 538-23-8
Endpoint summary
Administrative data
Description of key information
Additional information
Glycerol trioctanoate (CAS 538-23-8) is characterised by low water solubility (<0.532 µg/L at 20 °C and pH 6.3), low vapour pressure (≤ 3.8E-07 Pa at 20 °C, OECD 104), a high estimated log Koc (6.36, KOCWIN v2.00) and a high estimated log Kow (log Kow = 9.2, KOWWIN v1.68). Furthermore, the substance is considered readily biodegradable.
The substance is not volatile (VP ≤ 3.8E-07 Pa at 20 °C, OECD 104) and thus evaporation to the air and subsequent transport through the atmosphere to other environmental compartments is not likely.
Thus, soil and sediment are expected to be the main compartment for environmental distribution. According to the Guidance on Information Requirements and Chemical Safety Assessment, Chapter R.7b (ECHA, 2017), the ready biodegradability of a substance can be considered indicative of rapid and ultimate degradation in most environments, including biological sewage treatment plants (STP) where the substance will be extensively removed in the primary settling tank and fat trap. As a result of the high adsorption potential of the substance (log Koc > 6.36, MCI, KOCWIN v2.00) a removal from the water column to a significant degree by adsorption to sewage sludge can be expected (Guidance on information requirements and chemical safety assessment, Chapter R.7b, (ECHA, 2017)). Thus, only limited amounts will get in contact with activated sludge organisms in STPs and the concentration of the substance in effluents of conventional STPs is presumably marginal.
Due to ready biodegradability, abiotic degradation via hydrolysis is considered not relevant for the substance. The bioavailability of Glycerol trioctanoate (CAS 538-23-8) is expected to be low based on the predicted environmental fate and QSAR calculation. Due to the low water solubility and the ready biodegradability a relevant uptake and bioaccumulation in aquatic organisms is not expected.
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