Registration Dossier
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Diss Factsheets
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EC number: 946-260-7 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in soil
Administrative data
Link to relevant study record(s)
Description of key information
Biodegradation in soil
A test on biodegradation of tallow alkyl amine by soil microorganisms is available (Akzo Nobel, 1996). The bacteria were pre-adapted to the amine and isolated from soil. In two parallel tests, elimination percentages of 27 and 34% were determined after 2 days, while after 4 weeks 58 and 84% were eliminated. The test demonstrates that soil microorganisms are capable to degrade the amines. Because of the insufficient documentation and the probably unsuitable test system, the rates cannot be used for the exposure assessment.
According the REACH Guidance Document R.16 for the degradation rate in soil, the biodegradation half-life for a readily biodegradable substance depends on the sorption constant of the substance to soil e.g. if the Kpsoil is < 100 L/kg a half-life of 30 days is assigned. As the Kpsoil of 1-Octadecanamine was determined as 697 L/kg the assigned half-life would be 300 days. In reality also strongly sorbed substances may be biodegraded rapidly in soil as is demonstrated with the results from an Aerobic soil transformation study OECD 307.
An OECD 307 aerobic soil transformation study (3 soils) was carried out with [1-14C]-Hexadecanamine (Clariant, 2010). Although this C16 amine is strongly sorbing to soil (median Kpsoil of 3875 L/kg at lowest measured concentration) the following half-lives at 20 degree C were determined
Soil 1 t1/2 = 9.0 d
Soil 2 t1/2 = 8.1 d
Soil 3 t1/2 = 8.9 d
The recovery of the applied radiactivity was in the range of 91.2 -94.9%.
The median Half-life of 8.9 d at 20 degree C corresponds to a median Half-life of 16.9 d at an environmental temperature of 12 degree C (see REACH Guidance). This study demonstrates that 1-Hexadecanamine (C16 amine) is rapidly degraded in various soils and that the assumption of low degradation rates for strongly sorbing substances is unjustified.
Key value for chemical safety assessment
- Half-life in soil:
- 16.9 d
- at the temperature of:
- 12 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.