Registration Dossier
Registration Dossier
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EC number: 222-123-0 | CAS number: 3353-69-3
Endpoint summary
Administrative data
Description of key information
No acute oral and inhalation toxicity studies were available for the registered substance.
In accordance with Column 2 of REACH Annex VIII, the acute toxicity study via the oral route (required in Section 8.5.1) does not need to be conducted as the substance is classified as corrosive.
In accordance with Column 2 of REACH Annex VIII, the acute toxicity study via the inhalation route (required in Section 8.5.2) does not need to be conducted as the substance is classified as corrosive.
In accordance with Column 2 of REACH Annex VIII, the acute toxicity study via the dermal route (required in Section 8.5.3) does not need to be conducted as the substance is classified as corrosive.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
No acute oral, inhalation or dermal toxicity studies were available for the registered substance.
The supporting acute oral study on dichloro(3-chloropropyl)methylsilane (CAS 7787-93-1) is included to support the data waiver for repeated dose toxicity and reproductive and developmental toxicity testing via the oral route (see Section 5.6.4 of the Chemical Safety Report).
The supporting acute inhalation studies on trichloro(methyl)silane, trichloro(ethyl)silane and trichloro(propyl)silane are included to support the data waiver for repeated dose toxicity testing via the inhalation route (see Section 5.6.4 of the Chemical Safety Report).
Justification for classification or non-classification
No acute toxicity studies have been performed due to the corrosive nature of the substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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