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EC number: 202-169-8 | CAS number: 92-59-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Justification for type of information:
- Data is from Advisory Board for Environmentally Relevant Existing Substances (BUA)
- Qualifier:
- according to guideline
- Guideline:
- other: as mentioned below
- Principles of method if other than guideline:
- Biodegradation study was conducted for 28 days for evaluating the percentage biodegradability of test substance N-benzyl-N-ethylaniline.
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Name of test material: N-benzyl-N-ethylaniline
- Molecular formula: C15H17N
- Molecular weight: 211.306 g/mol
- Smiles notation: N(c1ccccc1)(Cc1ccccc1)CC
- InChl: 1S/C15H17N/c1-2-16(15-11-7-4-8-12-15)13-14-9-5-3-6-10-14/h3-12H,2,13H2,1H3
- Substance type: Organic
- Physical state: Liquid - Oxygen conditions:
- not specified
- Inoculum or test system:
- not specified
- Duration of test (contact time):
- 28 d
- Based on:
- not specified
- Parameter followed for biodegradation estimation:
- other: BOD
- Key result
- Parameter:
- other: BOD
- Value:
- 0
- Sampling time:
- 28 d
- Remarks on result:
- other: Other details not known
- Details on results:
- Test substance undergoes 0% degradation by BOD parameter in 28 days.
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The percentage degradation of test substance N-benzyl-N-ethylaniline was determined to be 0% by BOD parameter in 28 days. Thus, based on percentage degradation, N-benzyl-N-ethylaniline is considered to be not readily biodegradable in water.
- Executive summary:
Biodegradation study was conducted for 28 days for evaluating the percentage biodegradability of test substance N-benzyl-N-ethylaniline (CAS no.92-59-1).The percentage degradation of test substance N-benzyl-N-ethylaniline was determined to be 0% by BOD parameter in 28 days. Thus, based on percentage degradation, N-benzyl-N-ethylaniline is considered to be not readily biodegradable in nature.
Reference
Description of key information
Biodegradation study was conducted for 28 days for evaluating the percentage biodegradability of test substance N-benzyl-N-ethylaniline (CAS no.92-59-1) (Advisory Board for Environmentally Relevant Existing Substances (BUA), 2000).The percentage degradation of test substance N-benzyl-N-ethylaniline was determined to be 0% by BOD parameter in 28 days. Thus, based on percentage degradation, N-benzyl-N-ethylaniline is considered to be not readily biodegradable in nature.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
Various experimental study for the target compound N-benzyl-N-ethylaniline (CAS No. 92-59-1) and supporting weight of evidence studies for its read across substance were reviewed for the biodegradation end point which are summarized as below:
In an experimental study from secondary source (Advisory Board for Environmentally Relevant Existing Substances (BUA), 2000), biodegradation experiment was conducted for 28 days for evaluating the percentage biodegradability of test substance N-benzyl-N-ethylaniline (CAS no.92-59-1).The percentage degradation of test substance N-benzyl-N-ethylaniline was determined to be 0% by BOD parameter in 28 days. Thus, based on percentage degradation, N-benzyl-N-ethylaniline is considered to be not readily biodegradable in nature.
Another biodegradation study was conducted for evaluating the percentage biodegradability of test substance N-benzyl-N-ethylaniline (CAS no.92 -59 -1) (B.C.J. Zoeteman et. al; 1980). Rhine river surface water was used as a test inoculum obtained from Lobith or Gorinchem and the Rhine river surface water has a depth of approx. of 4 -5 meters. Initial test substance conc. used in the study was 0.001 mg/l, respectively. A careful sampling of Rhine water at Lobith was carried out for quantification of a wide range of chemicals in the water by means of GC-MS analyses of concentrates prepared by closed-loop gasstripping and XAD adsorption techniques. Assuming that reduction of the concentration of the chemicals takes place according to a first order overall process, the corresponding reaction constant and half-life was estimated from the observed drop in concentration during the known retention period. The percentage degradation of test substance N-benzyl-N-ethylaniline was determined to be 50% in 0.1 days (2.4 hrs). Thus, based on percentage degradation, N-benzyl-N-ethylaniline is considered to be readily biodegradable in nature.
In a supporting weight of evidence study from peer reviewed journal (H. Heukelekian and M. C. Rand, 1955) for the read across chemical N,N-diethylaniline (CAS no. 91-66-7), biodegradation experiment was conducted for 5 days for evaluating the percentage biodegradability of read across substance N, N-diethylaniline using standard dilution method at a temperature of 20°C. Sewage was used as a test inoculum. The 5 day BOD value of chemical N, N-diethylaniline was determined to be 0 g/g. Thus, based on this value, N, N-diethylaniline is considered to be not readily biodegradable in nature.
Additional biodegradation study was conducted for 5 days for evaluating the percentage biodegradability of read across substance N, N-diethylaniline (CAS no. 91-66-7) (HSDB, 2017). Sewage sludge was used as a test inoculum. The percentage degradation of substance N, N-diethylaniline was determined to be 5% by BOD parameter in 5 days. Thus, based on percentage degradation, N, N-diethylaniline is considered to be not readily biodegradable in nature.
For the same read across chemical N,N-diethylaniline (CAS no. 91-66-7) from authoritative database (J-CHECK and Envichem, 2017), biodegradation study was conducted for 14 days for evaluating the percentage biodegradability of read across substance N, N-diethylaniline. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. The percentage degradation of substance N, N-diethylaniline was determined to be 0% by BOD parameter in 14 days. Thus, based on percentage degradation, N, N-diethylaniline is considered to be not readily biodegradable in nature.
In a supporting weight of evidence study from authoritative database (J-CHECK, 2017) for the read across chemical N, N-dimethylaniline (CAS no. 121-69-7),biodegradation experiment was conducted for 14 days for evaluating the percentage biodegradability of read across substance N, N-dimethylaniline. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. The percentage degradation of substance N, N-dimethylaniline was determined to be1.9, 12.3 and 0% by BOD, TOC removal and GC parameter in 14 days. Thus, based on percentage degradation, N, N-dimethylaniline is considered to be not readily biodegradable in nature.
Although one study from peer reviewed journal ((B.C.J. Zoeteman et. al; 1980) indicate that the test chemical N-benzyl-N-ethylaniline is readily biodegradable in nature, but based on the secondary source (2000) in which the study has been carried out according to standard procedure and on the basis of above results for its read across substance (from authoritative database HSDB, J-CHECK, Envichem and peer reviewed journals), it can be concluded that the test substance N-benzyl-N-ethylaniline can be expected to be not readily biodegradable in nature.
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