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EC number: 216-472-8 | CAS number: 1592-23-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Data is from authorative database
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- according to guideline
- Guideline:
- other: as mentioned below
- Principles of method if other than guideline:
- WoE report is based on two long term toxicity study of aquatic invertebrate for the test chemical :
1. and 2. Long term toxicity study of test material was performed - GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): Calcium distearate
- Molecular formula (if other than submission substance): C36H70O4.Ca
- Molecular weight (if other than submission substance): 607.023 g/mol
- Smiles notation (if other than submission substance): CCCCCCCCCCCCCCCCCC(=O)O{-}.[Ca]{2+}.O{-}C(=O)CCCCCCCCCCCCCCCCC
- InChl (if other than submission substance): 1S/2C18H36O2.Ca/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2
- Substance type: Organic
- Physical state: Solid - Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- Daphnia magna
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 21 d
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 0.55 - < 2 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- 1.5 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Conclusions:
- The test chemical Calcium distearate is not likely to be toxic to invertebrate in long term atleast in the concentration range of 1.5 - 2 mg/l
- Executive summary:
Data available for the structurally read across chemicals has been reviewed to determine the short term toxicity of aquatic invertebrate of the test chemical Calcium distearate (1592 -23 -0).The studies are as mentioned below:
1.The long term studyof test material on aquatic invertebrate was performed to evalute its effect on reproduction efficiency of daphnia magna according to OECD Guideline 211 (Daphnia magna Reproduction Test). The EC50 of test material after 21 days was observed to be in the range of 0.66 - 2.1 mg/l . The no effect concentration (NOEC) was observed to be 0.66 mg/l .On the basis of above effect concentration test material can be considered toxic to aquatic enviroment, on the basis of EC50value it can be considered as non-toxic to fish and cannot be classified as hazardous as per the CLP criteria.
2.Long term toxicity of invertebrate study was performed for 21 days according to OECD Guideline 211 (Daphnia magna Reproduction Test). The effect concentration (EC50) observed after 21 days of long term study was observed to be 1.5 mg/l, the NOEC was observed to be 0.48 mg/l. On the basis of above valueit can be considered as non-toxic to fish and cannot be classified as hazardous as per the CLP criteria.
Reference
Description of key information
Long term toxicity to aquatic invertebrate:
Data available for the structurally read across chemicals has been reviewed to determine the short term toxicity of aquatic invertebrate of the test chemical Calcium distearate (1592 -23 -0).The studies are as mentioned below:
1.The long term studyof test material on aquatic invertebrate was performed to evalute its effect on reproduction efficiency of daphnia magna according to OECD Guideline 211 (Daphnia magna Reproduction Test). The EC50 of test material after 21 days was observed to be in the range of 0.66 - 2.1 mg/l . The no effect concentration (NOEC) was observed to be 0.66 mg/l .On the basis of above effect concentration test material can be considered toxic to aquatic enviroment, on the basis of EC50value it can be considered as non-toxic to fish and cannot be classified as hazardous as per the CLP criteria.
2.Long term toxicity of invertebrate study was performed for 21 days according to OECD Guideline 211 (Daphnia magna Reproduction Test). The effect concentration (EC50) observed after 21 days of long term study was observed to be 1.5 mg/l, the NOEC was observed to be 0.48 mg/l. On the basis of above valueit can be considered as non-toxic to fish and cannot be classified as hazardous as per the CLP criteria.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 1.5 mg/L
Additional information
Long term toxicity to aquatic invertebrate:
Data available for the structurally read across chemicals has been reviewed to determine the short term toxicity of aquatic invertebrate of the test chemical Calcium distearate (1592 -23 -0).The studies are as mentioned below:
1.The long term studyof test material on aquatic invertebrate was performed to evalute its effect on reproduction efficiency of daphnia magna according to OECD Guideline 211 (Daphnia magna Reproduction Test). The EC50 of test material after 21 days was observed to be in the range of 0.66 - 2.1 mg/l . The no effect concentration (NOEC) was observed to be 0.66 mg/l .On the basis of above effect concentration test material can be considered toxic to aquatic enviroment, on the basis of EC50value it can be considered as non-toxic to fish and cannot be classified as hazardous as per the CLP criteria.
2.Long term toxicity of invertebrate study was performed for 21 days according to OECD Guideline 211 (Daphnia magna Reproduction Test). The effect concentration (EC50) observed after 21 days of long term study was observed to be 1.5 mg/l, the NOEC was observed to be 0.48 mg/l. On the basis of above valueit can be considered as non-toxic to fish and cannot be classified as hazardous as per the CLP criteria.
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