Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Study period:
7 days
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Summary of study conducted. Not a full report. No discussion of controls provided.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1990
Report date:
1990

Materials and methods

Test type:
acute toxic class method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Name of test material (as cited in study report): DOB-AA

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
other: 1% Methocel
Doses:
5000 mg/kg given by oral gavage at 20 mL/kg body weight
No. of animals per sex per dose:
6 animals dosed
Control animals:
not specified

Results and discussion

Mortality:
0 of 6 dead at 5,000 mg/kg
Clinical signs:
No apparent food consumption in some animals through Day 3 of study

Applicant's summary and conclusion

Interpretation of results:
practically nontoxic
Remarks:
Migrated information Criteria used for interpretation of results: expert judgment
Conclusions:
No mortality to test animals at a concentration of 5,000 mg/kg for 7 day evaluation period