Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- The study was conducted between 23 October 2014 and 01 July 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Principles of method if other than guideline:
- As per the above mentioned guidelines
- GLP compliance:
- yes
- Type of method:
- flask method
- Specific details on test material used for the study:
- None
- Water solubility:
- 541 g/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- Remarks on result:
- other: Greater than 35.1 % w/w of solution (equivalent to greater than 541 g/L of water) at 20 °C.
- Details on results:
- Overall result: Greater than 35.1 % w/w of solution (equivalent to greater than 541 g/L of water) at 20.0 ± 0.5 °C.
- Conclusions:
- The water solubility of the test item has been determined to be greater than 35.1 % w/w of solution (equivalent to greater than 541 g/L of water) at 20.0 ± 0.5 °C.
- Executive summary:
The water solubility of the test substance was investigated in a study conducted according to OECD Guideline 105 and EU Method A.6. Flask method was used for this purpose. Based on the findings of the study, the water solubility of the test substance was determined to be greater than 35.1 % w/w of solution (equivalent to greater than 541 g/L of water) at 20.0 ± 0.5 °C.
Reference
The sample concentration, observations and solution pH for each sample are shown in the following table:
Sample |
Concentration (% w/w) |
Observations |
Solution pH |
1 |
5.3 |
Dark blue / black, very mobile liquid |
5.6 |
2 |
24.7 |
Dark blue / black, very mobile liquid |
* |
3 |
50.3 |
Dark blue / black, highly viscous liquid, plus a large lump of undissolved material |
* |
4 |
10.2 |
Dark blue / black, very mobile liquid |
4.9 |
5 |
15.0 |
Dark blue / black, very mobile liquid |
4.8 |
6 |
20.0 |
Dark blue / black, very mobile liquid |
5.0 |
7 |
30.0 |
Dark blue, highly mobile liquid |
4.6 |
8 |
35.1 |
Dark blue / black, highly mobile liquid |
4.3 |
9 |
40.0 |
Dark blue / black liquid. Significantly more viscous than Samples 7 and 8 |
* |
* Not performed, typically due to lack of enough solution phase.
Description of key information
The water solubility of the test substance was determined to be greater than 35.1 % w/w of solution (equivalent to greater than 541 g/L of water) at 20.0 ± 0.5 °C.
Key value for chemical safety assessment
- Water solubility:
- 541 g/L
- at the temperature of:
- 20 °C
Additional information
The water solubility of the test substance was investigated in a study conducted according to OECD Guideline 105 and EU Method A.6. Flask method was used for this purpose. Based on the findings of the study, the water solubility of the test substance was determined to be greater than 35.1 % w/w of solution (equivalent to greater than 541 g/L of water) at 20.0 ± 0.5 °C.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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