Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 436-900-9 | CAS number: 39290-90-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 18 October 2000-02 May 2001
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study has been performed according to OECD and EC guidelines and according to GLP principles.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 001
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.1 (Acute Toxicity for Fish)
- Version / remarks:
- (1992)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Version / remarks:
- (1992)
- GLP compliance:
- yes
Test material
- Reference substance name:
- -
- EC Number:
- 436-900-9
- EC Name:
- -
- Cas Number:
- 39290-90-9
- Molecular formula:
- Hill Empirical formula: K(0.2-0.7) Mg(0.4) Ti(1.6) O(3.7-3.95) CAS Empirical formula: K(0.2-0.7) Mg(0.4) Ti(1.6) O(3.7-3.95)
- IUPAC Name:
- Magnesium Potassium Titanium Oxide
- Details on test material:
- Batch: 0G99
White powder
Expiry date: 21 August 2001
Test substance storage: At room temperature in the dark
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- - Concentrations: 0 (control) and 100 mg/L nominal (filtered and unfiltered)
- Sampling method: 10 mL from the approximate centre of the test vessels
- Sample storage conditions before analysis: in a deep freeze until shipment to Solvias AG, Basel, Switzerland.
Test solutions
- Vehicle:
- no
- Details on test solutions:
- Supersaturated solutions were prepared at nominally 100 mg/L and magnetically stirred for three days to achieve
maximum solubility. Then, two of the solutions were filtered
through a paper filter to remove the larger undissolved test
substance particles (ca. > 5 µm). The filtered solution
was used to prepare three lower concentrations (0.1, 1 and 10% of the filtrate) . The
other solution was not filtered and used as such (100 mg/L nominal).
The unfiltered solution was a turbid whitish dispersion with undissolved test substance particles. The undiluted filtered solution was slightly turbid, while the dilutions of the filtrate were clear and colourless.
Test organisms
- Test organisms (species):
- Cyprinus carpio
- Details on test organisms:
- TEST ORGANISM
- Common name: Carp
- Strain: Cyprinus carpio, Teleostei, Cyprinidae
- Source: Zodiac, proefacc, "De Haar Vissen", L.U. Wageningen, the Netherlands.
- Length at study initiation (length definition, mean, range and SD): 2.14 ± 0.12 cm
- Weight at study initiation (mean and range, SD): 0.24 ± 0.05 g
- Method of breeding: F1 from a single parent-pair bred in UV-treated water.
- Feeding during test: No feeding from 48 hours prior to the test and during the total test period.
ACCLIMATION
- Acclimation period: at least 12 days after delivery
- Acclimation conditions (same as test or not): yes
- Type and amount of food: Trouvit
- Feeding frequency: Daily
- Health during acclimation (any mortality observed): In the batch of fish used for the test, mortality during the seven days prior to the start of the test was less than 5%.
NUMBER OF FISH
100 mg/l filtered and unfiltered and control: 7 fish per test group.
dilutions: 3 fish per test group.
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 96 h
Test conditions
- Hardness:
- 250 mg CaCO3/L
- Test temperature:
- Blank control: 20.8 (day 0) - 21.0 (day 4)
100% filtrate: 20.9 (day 0) - 20.5 (day 4)
100 mg/l: 20.6 (day 0) - 20.5 (day 4) - pH:
- Blank control: 8.0 (day 0) - 7.6 (day 4)
100% filtrate: 8.9 (day 0) - 7.7 (day 4)
100 mg/l: 9.0 (day 0) - 7.8 (day 4) - Dissolved oxygen:
- Blank control: 9.3 (day 0) - 7.6 (day 4) mg/l
100% filtrate: 7.4 (day 0) - 7.4 (day 4) mg/l
100 mg/l: 9.0 (day 0) - 7.7 (day 4) mg/l - Nominal and measured concentrations:
- A filtered and unfiltered solution prepared at nominally 100 mg/l and dilutions of the filtrate containing 0.1, 1.0 and 10% filtrate.
Blank-control Test medium without test substance or other additives (0 mg/l).
Analysis of the samples taken from the unfiltered test solution showed that the titanium concentration measured in the water phase decreased during the test period from 19420 µg/l to 28 µg/l after 96 hours. This was due to precipitation and deposition of the undissolved test substance particles. The concentration measured in the filtered test solution decreased from 2688 µg/l to 146 µg/l during the test period. This could be due to the fact that filtration had not been complete. Hence, measured concentrations in both the filtered and unfiltered solution remained above the calculated water solubility (< 10 µg/l based on titanium corresponding with < 36 µg/l for TERRACESS P). - Details on test conditions:
- The test media were not aerated during the test.
16 hours photoperiod daily
Loading: 100 mg/L filtered and unfiltered and control: 0.34 g fish/L, i.e. 7 fish per 5 litres of test medium. Dilutions: 0.24 g fish/L, i.e. 3 fish per 3 litres of test medium. - Reference substance (positive control):
- yes
- Remarks:
- pentachlorophenol
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 1 417 µg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- element
- Remarks:
- titanium
- Basis for effect:
- mortality (fish)
- Details on results:
- During the 96-hour test period no visible effects were observed in any of the concentrations tested. The test substance induced no visible effects in carp when exposed to a filtered or an unfiltered solution prepared at 100 mg/L. Owing to the extremely poor solubility of the test substance in water, concentration levels toxic for fish could not be reached. Therefore, the 96h-LC50 for Carp exceeded the maximum solubility of TERRACESS P in water at a loading of 100 mg/L, the regulatory limit concentration.
- Results with reference substance (positive control):
- The 96h-LC50 for carp exposed to the reference substance was already reached after 48 hours of exposure and was 0.14 mg/L with a 95 % confidence interval between 0.13 and 0.18 mg/L.
- Reported statistics and error estimates:
- The range of the 96h-LC50 for carp is generally between 0.10 and 0.46 mg/L based on historical data.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The calculated 96h-LC50 for Carp is > 1417 ug/L. This is an avearge of the measured Ti concentrations in the filtered test solutions that decreased from 2866 ug/L to 146 ug/L during the test period. The calculated 96h-LC50 is 5141 ug Terraces P/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.