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Diss Factsheets
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EC number: 225-897-8 | CAS number: 5137-70-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
For skin irriration, one study on an analogue was available (Reliabilty 2 (Allen, 1997)
No study available for eye irritation
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (corrosive)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Skin irritation / Corrosion
In the study of Allen (Key study, 1997), exposure of one rabbit for 1 or 2 hours produced severe erythema (grade 4) and oedema (grade 3) at 24 hours. Effects indicating dermal corrosion prevented evaluation of erythema or oedema at 48 and 72 hours. Effects persisted to termination of the study at 12 days.
Eye irritation.
As DodecylPhosphonic acid was considered to be corrosive to the skin, no study on eye was performed
Justification for selection of skin irritation / corrosion endpoint:
Only one study available on an analogue.
Effects on skin irritation/corrosion: corrosive
Justification for classification or non-classification
Skin:
Corrosive effects from 1, 2 or 4 hour exposures were not fully resolved by end of the 12 day observation period. No corrosive effects were reported for a 3-minute exposure. Based on these results on OPA, DodecylPhosphonic Acid is classified as Corrosive, Category 1B (H314: causes severe skin burns and eye damage) according to the criteria of the Regulation (EC) 1272/2008 and as skin corrosive (C-R34) according to the criteria of the Annex VI of the Directive 67/548/EEC.
Eye:
According to the criteria of the Regulation (EC) 1272 / 2008, DodecylPhosphonic Acid is classified as causing serious eye damage, category 1 (implicit in skin corrosion classification).
Respiratory System:
No classification is possible due to lack of data.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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