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Diss Factsheets
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EC number: 810-490-5 | CAS number: 35501-23-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: The study was conducted according to an OECD test guideline and in accordance with a recognised quality system.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 014
- Report date:
- 2014
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 111 (Hydrolysis as a Function of pH)
- Deviations:
- no
- GLP compliance:
- no
Test material
- Reference substance name:
- N-butyl-N-[(triethoxysilyl)methyl]butan-1-amine
- EC Number:
- 810-490-5
- Cas Number:
- 35501-23-6
- Molecular formula:
- C15H35NO3Si
- IUPAC Name:
- N-butyl-N-[(triethoxysilyl)methyl]butan-1-amine
Constituent 1
- Radiolabelling:
- no
Study design
- Analytical monitoring:
- yes
- Details on sampling:
- For the 1H NMR measurement 850 μl of the buffer solutions containing about 5 μl of “Silan
DBA-TEO” (pH 4.0, pH 7.0, pH 9.0 respectively) were mixed with 150 μl of deuterated water
(D2O), containing 3-trimethylsilylpropionic acid, sodium salt, 2,2,3,3-tetradeuterated
(Na-TSP-d4) as shift and internal standard in a 5 mm NMR sample tube. - Buffers:
- pH 4.0: CertiPur, Citric acid + hydrochloric acid + sodium hydroxide, company Merck
pH 7.0: Baker Analyzed, Potassium dihydrogen phosphate + disodiumhydrogen phosphate, company J. T. Baker
pH 9.0: CertiPur, Boronic acid + potassium chloride + sodium hydroxide, company Merck - Details on test conditions:
- Medium: Water-d2 / Na-TSP-d4 (5006.46 mg D2O + 21.53 mg Na-TSP-d4)
Temperature: 25 °C
Duration of experiment: About 1 h for each buffered sample
Analysis: 1H NMR
Equipment: Bruker Avance 400, 5 mm ATM BBI probehead with z-gradients
Acquisition parameters:
Pulse program zg
NS 1
DS 0
TD 64k
SWH 8012 Hz
TE 298 K
Processing parameters:
SI 64k
WDW EM
LB 0.3 Hz
D1 6 sec
Results and discussion
Dissipation DT50 of parent compoundopen allclose all
- pH:
- 4
- Temp.:
- 25 °C
- DT50:
- < 2 min
- pH:
- 7
- Temp.:
- 25 °C
- DT50:
- < 2 min
- pH:
- 9
- Temp.:
- 25 °C
- DT50:
- < 2 min
- Details on results:
- At all examined pH values only signals of N,N-dibutylaminomethylsilanetriol and ethanol
could be observed after the first measurement. There was no signal of ethoxysilane detectable.
Therefore it was concluded that hydrolysis was already completed when the first
spectrum of these pH series was measured.
Because hydrolysis was finished after the first 1H NMR measurement (about 2 minutes after
mixing the test sample) no exact half-life time or reaction rate could be calculated.
Any other information on results incl. tables
End point | Result | pH value measured after end of hydrolysis / end of experiments |
Half-life time in pH 4 buffer solution | << 2 min | 4.5 |
Half-life time in pH 7 buffer solution | << 2 min | 7.4 |
Half-life time in pH 9 buffer solution | << 2 min | 9 |
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.