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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
no data
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Limited publication.

Data source

Reference
Reference Type:
publication
Title:
The place of the range-finding test in the industrial toxicology laboratory.
Author:
Smyth, H.F. Jr., Carpenter, C.P.
Year:
1944
Bibliographic source:
J IND HYG 26:269-273, 1944.

Materials and methods

Principles of method if other than guideline:
no information

Test material

Constituent 1
Chemical structure
Reference substance name:
Citraconic anhydride
EC Number:
210-459-0
EC Name:
Citraconic anhydride
Cas Number:
616-02-4
Molecular formula:
C5H4O3
IUPAC Name:
3-methyl-2,5-dihydrofuran-2,5-dione
Details on test material:
citraconic anhydride

Test animals

Species:
rat

Results and discussion

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Conclusions:
Inhalation of air saturated with vapor for 4 hours does not result in deaths. Outcome comparable to that of benzyl alcohol.
Executive summary:

Inhalation of air saturated with vapor for 4 hours does not result in deaths. Outcome comparable to that of benzyl alcohol.