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EC number: 627-071-6 | CAS number: 1233873-37-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
NOEC (91d) = 0.006 mg/L (measured) for Oncorhynchus mykiss (ASTM E 1241-05, read across)
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 0.006 mg/L
Additional information
Since no study assessing the long-term toxicity of Benzaldehyde, 2-hydroxy-5 -dodecyl, oxime, branched (CAS 1233873-37-4) to fish is available, in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 Grouping of substances, a read-across to Phenol, 4-nonyl-,branched (CAS 84852-15-3) was conducted, which is structurally similar to the main component of the substance. The structural difference between the source substance and the target substance is the lack of a aldoxime group at the phenol ring of the molecule and a C9 branched carbon chain instead of a C12 branched carbon chain. The read across is justified by similarity of structure and functional groups and accordingly similar physico-chemical properties, which is expected to result in similar environmental behavior and fate (see table).
Substance |
Benzaldehyde, 2-hydroxy-5 -dodecyl, oxime, branched |
Phenol, 4-nonyl, branched* |
CAS number |
1233873-37-4 |
84852-15-3 |
Structure |
see attachment (chapter 6.1) |
see attachment (chapter 6.1) |
Molecular formula |
C19H31N1O2 |
C15H24O |
Molecular weight |
~305.46 g/mole |
~ 220.35 g/mole |
PC parameter |
|
|
Water solubility |
0.3 mg/L (OECD 105) |
5.7 mg/L (ASTM E 1148-02) |
Partition coefficient |
> 5.7 (EU method L3B3 A/63 -73) |
5.4 (OECD 117) |
Vapour pressure |
< 0.39 Pa at 20 °C (estimation based on grain-Watson method) |
~1 Pa at 20 °C (ASTM-D 2879) |
Environmental fate |
|
|
Biodegradability |
- |
non-adapted inoculum: 0 % in 28 days (OECD 301B)
adapted inoculum: 48.2-62 % in 28 days (OECD 301B) |
Adsorption [log KOC] |
4.4 (OECD 121) |
4.35 - 5.69 (EPA OTS 796.2750) |
Hydrolysis |
not relevant |
|
Ecotoxicology |
|
|
Short-term toxicity to fish [96h-LC50] |
- |
0.05 – 0.22 mg/L (different methods) |
Long-term toxicity to aquatic invertebrates [NOEC] |
- |
0.006 mg/L (ASTM E 1241-05) |
Short-term toxicity to aquatic invertebrates [48h-EC50] |
- |
0.08 – 0.14 mg/L (different methods) |
Long-term toxicity to aquatic invertebrates [21d-NOEC] |
- |
0.024 - 0.116 mg/L (different methods) |
Short-term toxicity to algae [72h-EC50] |
498.32 mg/L (OECD 201) |
0.33 - 1.3 mg/L (different methods) |
Long-term toxicity to algae [72h-NOEC/EC10] |
101.2 mg/L (OECD 201) |
0.5 mg/L (Algal growth inhibition test according to UBA 1984) |
Toxicity to microorganisms [EC50] |
- |
950 mg/L (OECD 209) |
* Data were taken from Phenol, 4-nonyl-,branched (CAS 84852-15-3) dossier published on the ECHA data base
The available study investigated the long-term toxicity of 4-nonylphenol to early life stage of rainbow trout (Oncorhynchus mykiss) under flow through conditions (Spehar et al. 2010). The study was performed according to ASTM guideline E 1241-05 over an exposure time of 91 days. 100 fertilized eggs per test concentration were exposed to measured concentrations of 6.0, 10.3, 23.1, 53.0 and 114 µg/L 4-nonylphenol. The test system was maintained at ~ 11 ºC and a pH of 6.97. Mean percent hatch of any test concentration was not significantly different from controls. Time to hatch was 39 ± 5 days with swim-up at approximately at day 45. The most sensitive end point was growth. The 91-day NOEC value, based on sublethal effects (growth measured by mean standard length, wet weight and dry weight) is determined to be 6.0 µg/L.
Based on the reasons given above this value is considered to be sufficiently conservative to be used for PNEC derivation of Benzaldehyde, 2-hydroxy-5 -dodecyl, oxime, branched (CAS 1233873-37-4).
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