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EC number: 635-156-4 | CAS number: 109293-98-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water and sediment: simulation tests
Administrative data
Link to relevant study record(s)
Description of key information
The anaerobic aquatic metabolism of 14C-labelled test substance (diflufenzopyr) was studied in sediment and pond water. During the study the primary metabolite (difluoroaniline metabolite) reached a maximum concentration of 22% TAR (total applied radioactivity) by day 61 and decreased to 1% TAR by 187 DAT. The DT50 of the metabolite difluoroaniline was 27.4 days. The intermediate metabolite BH 654-5 ranged from 0.6% to 8% TAR and at 187 DAT accounted for less than 1% TAR. The present study showed that the test substance is rapidly degraded under anaerobic conditions. The DT50 of the test substance was reported to be about 7.5 days. The half-lives in water and sediment were determined to be 5.75 d at 25 °C and 7.87 d at 25 °C, respectively.
Key value for chemical safety assessment
- Half-life in freshwater:
- 5.75 d
- at the temperature of:
- 25 °C
- Half-life in freshwater sediment:
- 7.87 d
- at the temperature of:
- 25 °C
Additional information
The anaerobic aquatic metabolism of 14C-labelled test substance (diflufenzopyr) was studied in sediment and pond water in accordance with EPA Pesticide Assessment Guidelines, Subdivision N, 162-3, "Anaerobic Aquatic Metabolism" and Canadian Trade Memorandum T-l-255, DACO 8.2.3.5.5 and 8.2.3.5.6.
Under anaerobic conditions, the test substance was rapidly degraded and dispersed from the water after treatment. The radioctivity in the water layer declined with time. In the 0.4 ppm system, the radioactivity in the water phase declined steadily from an initial value of 101 % TAR (0 DAT, days after treatment) to 2% TAR after 9 months of incubation (270 days after treatment). In the sediment, the radioactivity increased after 15 days of incubation to about 26% TAR. Mineralization and other volatiles accounted for less than 0.5% TAR.
Bound residues increased from 4% TAR at 0 DAT to 83% TAR at 270 DAT. Characterization of the bound residues revealed that about 53% of these residues could be attributed to the fulvic acid and humic acid fractions.
A significant degradation of the test substance occurred under anaerobic conditions and this was accompanied by formation of BH 654-5 and BH 654-2. Metabolite difluoroaniline was formed rapidly under anaerobic conditions and reached a maximum concentration of 22% TAR by 61 days. BH 654-2 decreased to 1.1% TAR after 6 months (187 DAT).
The test substance was detected in the sediment and reached a maximum concentration after 3 months. Several unknown metabolites were detected in the sediment and none of them accounted for more than 5% TAR.
Disappearance times for test substance and the major metabolite BH 654-2 were calculated separately for each phase (water, sediment and total water and sediment). The DT50 of the parent in the total system was about 7.5 days. The DT50 of the major metabolite, BH 654-2 (difluoroaniline), in the total system was 27.4 days. The half-lives in water and sediment were determined to be 5.75 d at 25 °C and 7.87 d at 25 °C, respectively.
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