Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Reliable authoritative secondary source

Data source

Reference
Reference Type:
publication
Title:
Ethanol Potentiates the Toxic Effects of 1,4-Butanediol
Author:
Poldrugo, F., et. al.
Year:
1985
Bibliographic source:
Poldrugo, F., et. al., Ethanol Potentiates the Toxic Effects of 1,4-Butanediol. Alcoholism: Clinical and Experimental Research. 9, pp. 493-497.

Materials and methods

GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Butane-1,4-diol
EC Number:
203-786-5
EC Name:
Butane-1,4-diol
Cas Number:
110-63-4
Molecular formula:
C4H10O2
IUPAC Name:
butane-1,4-diol

Results and discussion

Any other information on results incl. tables

Simultaneous administration of ethanol and 1,4 -Butanediol potentiates the toxic effects of 1,4 -Butanediol.

Applicant's summary and conclusion