Registration Dossier
Registration Dossier
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EC number: 231-818-8 | CAS number: 7757-79-1
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- other: overview article
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Nitrate WHO Food Additives Series
- Author:
- World Health Organization
- Year:
- 1 996
- Bibliographic source:
- Nitrate WHO Food Additives Series; p. 325-60
Materials and methods
- Type of study / information:
- no data
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- no data
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Potassium nitrate
- EC Number:
- 231-818-8
- EC Name:
- Potassium nitrate
- Cas Number:
- 7757-79-1
- Molecular formula:
- HNO3.K
- IUPAC Name:
- potassium nitrate
- Test material form:
- solid: crystalline
- Details on test material:
- Name of test material: potassium nitrate (KNO3)
Physical appearance: colourless crystalline solid or a white crystalline or granular powder
Constituent 1
Method
- Details on study design:
- no data
- Exposure assessment:
- not specified
Results and discussion
- Results:
- Single oral doses of 25-170 mg potassium nitrate given to humans resulted in a urinary nitrate excretion of 65-70% irrespective of the dose. Excretion was maximal 5 h after ingestion and returned to baseline levels within 18 h.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
