Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 206-557-8 | CAS number: 354-33-6
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Additional information:
- Migrated from Short description of key information:
No dedicated studies are available for the evaluation of the sensitising potential of HFC 125. However, no signs of skin sensitisation were observed in experimental animals exposed up to 50000 ppm HFC 125 in the atmosphere for 13 consecutive weeks.
Respiratory sensitisation
Endpoint conclusion
- Additional information:
- Migrated from Short description of key information:
No dedicated studies are available for the evaluation of the sensitising potential of HFC-125. However, no signs of respiratory sensitisation were observed in experimental animals exposed by inhalation up to 50000 ppm HFC-125 in the atmosphere for 13 consecutive weeks.
Justification for classification or non-classification
HFC-125 can be considered as a non-sensitising substance and no classification is deemed necessary.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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