Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-104-9 | CAS number: 115-77-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2010
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Remarks:
- The study was conducted in accordance with OECD test guidelines, however no claim of GLP compliance was made, and a number of deviations from the guideline were recorded. The demands in the guideline regarding sterility and temperature variation (50 ± 0.5 °C) are not met (the heating cabinet manual states that the temperature is within ±0.4°C, however not checked), but considered to be of little significance to the result. The product was considered hydrolytically stable and if the result from the study would have shown that the product was hydrolytically instable we would have let a GLP certified laboratory run a further tests.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 111 (Hydrolysis as a Function of pH)
- Deviations:
- no
- GLP compliance:
- not specified
- Remarks:
- The demands in the guideline regarding sterility and temperature variation (50 ± 0.5 °C) are not met (heating cabinet manual states that the temperature is within ±0.4°C, however not checked), but considered to be of little significance to the result.
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material:
- Water solubility: Completely soluble at 20°C. - Radiolabelling:
- no
- Analytical monitoring:
- yes
- Details on sampling:
- - Sampling intervals for the parent/transformation products: Samples were analysed after 5 days storage, for the parent compounds.
- Sampling method: Samples were allowed to reach room temperature then injected onto HPLC without dilution. - Buffers:
- - pH: 4±0.01 (20°C)
- Composition of buffer: citric acid/sodium hydroxide/hydrogen chloride
- pH: 7±0.01 (20°C)
- Composition of buffer: di-sodium hydrogen phosphate/potassium di-hydrogen phosphate
- pH: 9±0.01 (20°C)
- Composition of buffer: boric acid/potassium chloride/sodium hydrogen - Duration:
- 5 d
- pH:
- 4
- Temp.:
- 50 °C
- Duration:
- 5 d
- pH:
- 7
- Temp.:
- 50 °C
- Duration:
- 5 d
- pH:
- 9
- Temp.:
- 50 °C
- Number of replicates:
- Duplicate measurements at each pH.
- Positive controls:
- no
- Negative controls:
- no
- Preliminary study:
- Pentaerythritol was shown to be hydrolytically stable during the preliminary test (conducted at a temperature of 50°C), and was therefore determined to be stable to hydrolysis.
- Transformation products:
- not measured
- Remarks on result:
- hydrolytically stable based on preliminary test
- Remarks on result:
- hydrolytically stable based on preliminary test
- Validity criteria fulfilled:
- not specified
- Conclusions:
- No sign of hydrolysis was seen under the conditions investigated.
- Executive summary:
A hydrolysis study was conducted by Perstorp AB, to determine the hydrolysis in water at different pH values of the test substance Pentaerythritol. The study was conducted according to the OECD 111 test guideline.
Solutions of the test substance in aqueous buffers at pHs 4, 7 and 9 were stored in a heating cabinet at 50°C for five days. At the end of the storage period, the samples at 50°C were analysed with samples which had been stored at -20°C, and the difference calculated.
It was concluded that no sign of hydrolysis was seen under the conditions investigated.
Reference
% Change in content of components:
(Difference found between sample stored at -20°C and +50°C after 5 days)
Pentaerythritol:
pH 4 - -0.6%, -2.4%
pH 7 - 0.7%, -5.6%
pH 9 - 2.8%, -5.5%
Description of key information
The substance pentaerythritol is stable to hydrolysis i.e. the estimated half-life of the components is greater than one year under typical environmental conditions.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.