Nickel sulphate

GHS

General Information

Implementation:

EU

Type of classification:

harmonised classification

Remarks:

• Acute oral toxicity. A newly conducted GLP OECD guideline compliant study reported an LD50 =361 mg/kg for Ni sulfate hexahydrate, which confirms classification for acute oral toxicity under the 1st ATP to the CLP (EPSL, 2009).
  
• Acute inhalation toxicity. As data were not available at the time of classification, the EU Risk Assessment based the classification for acute inhalation toxicity on read-across from the oral data. However, a newly conducted GLP OECD guideline compliant study reported an LC50 =2.48 mg/L for Ni sulfate hexahydrate, which confirm the classification for acute inhalation toxicity under the 1st ATP to the CLP Regulation (EPSL, 2009).

Related composition

Related composition:

Nickel sulphate (anhydrous form)

Nickel sulphate (hydrates)

Nickel sulphate (anhydrous form) - company specific

Classification

Physical hazards

Explosives

Reason for no classification:

data conclusive but not sufficient for classification

Flammable gases and chemically unstable gases

Reason for no classification:

data conclusive but not sufficient for classification

Aerosols

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

hazard class not assessed

Oxidising gases

Reason for no classification:

data conclusive but not sufficient for classification

Gases under pressure

Reason for no classification:

data conclusive but not sufficient for classification

Flammable liquids

Reason for no classification:

data conclusive but not sufficient for classification

Flammable solids

Reason for no classification:

data conclusive but not sufficient for classification

Self-reactive substances and mixtures

Reason for no classification:

data conclusive but not sufficient for classification

Pyrophoric liquids

Reason for no classification:

data conclusive but not sufficient for classification

Pyrophoric solids

Reason for no classification:

data conclusive but not sufficient for classification

Self-heating substances and mixtures

Reason for no classification:

data conclusive but not sufficient for classification

Substances and mixtures which in contact with water emit flammable gases

Reason for no classification:

data conclusive but not sufficient for classification

Oxidising liquids

Reason for no classification:

data conclusive but not sufficient for classification

Oxidising solids

Reason for no classification:

data conclusive but not sufficient for classification

Organic peroxides

Reason for no classification:

data conclusive but not sufficient for classification

Corrosive to metals

Reason for no classification:

data lacking

Desensitized explosives

Reason for no classification:

data lacking

Health hazards

Acute toxicity - oral

Hazard category:

Acute Tox. 4

Hazard statement:

H302: Harmful if swallowed.

Acute toxicity - dermal

Reason for no classification:

data conclusive but not sufficient for classification

Acute toxicity - inhalation

Hazard category:

Acute Tox. 4

Hazard statement:

H332: Harmful if inhaled.

Skin corrosion / irritation

Hazard category:

Skin Irrit. 2

Hazard statement:

H315: Causes skin irritation.

Serious eye damage / eye irritation

Reason for no classification:

data conclusive but not sufficient for classification

Respiratory sensitisation

Hazard category:

Resp. Sens. 1

Hazard statement:

H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.

Skin sensitisation

Hazard category:

Skin Sens. 1

Hazard statement:

H317: May cause an allergic skin reaction.

Aspiration hazard

Reason for no classification:

data lacking

Reproductive toxicity

Hazard category:

Repr. 1B

Hazard statement:

H360D: May damage the unborn child.

Specific effect:

Perinatal mortality

Effects on or via lactation

Reason for no classification:

data conclusive but not sufficient for classification

Germ cell mutagenicity

Hazard category:

Muta. 2

Hazard statement:

H341: Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.

Carcinogenicity

Hazard category:

Carc. 1A

Hazard statement:

H350i: May cause cancer by inhalation.

Route of exposure:

inhalation

1. Specific target organ toxicity - single (STOT-SE)

Reason for no classification:

data conclusive but not sufficient for classification

1. Specific target organ toxicity - repeated (STOT-RE)

Hazard category:

STOT Rep. Exp. 1

Hazard statement:

H372: Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.

Affected organs:

other: Respiratory tract only

Route of exposure:

inhalation

Specific concetration limits

1.

Concentration range (%):

>= 20

Hazard categories:

Skin Irrit. 2

2.

Concentration range (%):

>= 0.01

Hazard categories:

Skin Sens. 1

3.

Concentration range (%):

>= 1

Hazard categories:

STOT Rep. Exp. 1

4.

Concentration range (%):

>= 0.1 - < 1

Hazard categories:

STOT Rep. Exp. 2

Environmental hazards

Hazardous to the aquatic environment (acute / short-term)

Hazard category:

Aquatic Acute 1

Hazard statement:

H400: Very toxic to aquatic life.

Hazardous to the aquatic environment (long-term)

Hazard category:

Aquatic Chronic 1

Hazard statement:

H410: Very toxic to aquatic life with long lasting effects.

M-Factor acute:

1

M-Factor chronic:

1

Hazardous to the ozone layer

Reason for no classification:

data conclusive but not sufficient for classification

Labelling

Signal word:

Danger

Hazard pictogram

GHS08: health hazard

GHS07: exclamation mark

GHS09: environment

Hazard statements

H350i: May cause cancer by inhalation.

H341: Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.

H360D: May damage the unborn child.

Perinatal mortality

H372: Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.

Affected organs: Respiratory tract only; Route of exposure: Inhalation

H332: Harmful if inhaled.

H302: Harmful if swallowed.

H315: Causes skin irritation.

H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.

H317: May cause an allergic skin reaction.

H410: Very toxic to aquatic life with long lasting effects.