2,3-epoxypropyltrimethylammonium chloride

Adsorption / desorption

Administrative data

Endpoint:

adsorption / desorption

Remarks:

adsorption

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: The study was conducted in accordance with generally accepted scientific principles and in compliance with GLP.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2006

Report date:

2006

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: OECD 303A

Deviations:

no

Principles of method if other than guideline:

The adsorption coefficient was determined by analytical measurment of test substance concentrations in water and sludge on six test days during the course of an OECD 303A simulation study.

GLP compliance:

yes (incl. QA statement)

Type of method:

other: Adsorption measured during OECD 303A simulation study

Media:

sewage sludge

Test material

Test material information

Constituent 1

Reference substance name:

2,3-epoxypropyltrimethylammonium chloride

EC Number:

221-221-0

EC Name:

2,3-epoxypropyltrimethylammonium chloride

Cas Number:

3033-77-0

Molecular formula:

C6H14NO.Cl

IUPAC Name:

N,N,N-trimethyl(oxiran-2-yl)methanaminium chloride

Details on test material:

- Name of test material (as cited in study report): 2,3-epoxypropyltrimethylammonium chloride

- Physical state: Liquid

- Analytical purity: 73.1%

- Impurities (identity and concentrations): 1.4% 3-chloropropryltrimethylammonium chloride (CHPTAC); 19 mg/kg total other impurities; remainder water

- Purity test date: 2005-03-31

- Lot/batch No.: 153897

- Expiration date of the lot/batch: September 2005

- Stability under test conditions: Hydrolyses slowly

- Storage condition of test material: 12-15°C, protected from light

Radiolabelling:

no

Study design

Test temperature:

20±2 °C

Batch equilibrium or other method

Analytical monitoring:

yes

Details on sampling:

Sampling was carried out on days 57, 61, 64, 111, 112 and 113 of the test.

Details on matrix:

Test matrix was sewage effluent and sludge from an OECD 303A simulation study.

Computational methods:

Kpsludge = conc. in sludge/conc. in water

Although the organic carbon content of the sludge was not measured during the test, it has been assumed that the proportion of the organic carbon in sludge is 50 %.

Results and discussion

Adsorption coefficient

Type:

Koc

Value:

53.8

Applicant's summary and conclusion

Validity criteria fulfilled:

not applicable

Conclusions:

As part of an OECD 303A degradation simulation study, measured concentrations of EPTAC in sludge and water were used to determine the Koc based on an assumed organic carbon content of 50%. The measured Koc was 53.8 kg/l.