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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 201-195-7 | CAS number: 79-31-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Henry's Law constant
Administrative data
Link to relevant study record(s)
- Endpoint:
- Henry's law constant
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable, well-documented publication which meets basic scientific principles
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Determination of thermodynamic Henry's law constants by equilibrium partial pressure measurements over aqueous solutions at 298.15 K
- GLP compliance:
- no
- H:
- 1 130 other: mol/atm kg
- Temp.:
- 25 °C
- Conclusions:
- For isobutyric acid, an experimetal HLC of 8.84E-7 atm m³/mol was determined in a study according to accepted scientific principles
- Executive summary:
For isobutyric acid, a Henry's law constant of 8.85E-7 atm m³/mol was determined in a study using equilibrium partial pressure measurements over aqueous solutions at 298.15 (25°C).
Reference
The reported value is equivalent to 8.85E-7 atm m³/mol.
Description of key information
measured HLC (25°C) = 8.85E-7atm*m3/mol (0.08967 Pa*m3/mol) (method: equilibrium partial pressure measurements over aqueous solutions)
Key value for chemical safety assessment
- Henry's law constant (H) (in Pa m³/mol):
- 0.09
- at the temperature of:
- 20 °C
Additional information
For isobutyric acid, a Henry's law constant of 8.85E-7 atm m³/mol was determined in a study using equilibrium partial pressure measurements over aqueous solutions at 298.15 K (25°C) (Khan, 1992).
A calculated Henry's law constant of 9.65E-007 atm*m3/mol (bond contribution method) and of 9.09E-007 atm*m3/mol (group contribution method) was obtained using the program HENRYWIN v 3.2 (Part of US EPA EPI Suite v4.00) (ECT, 2009). Measured and calculated HLC match satisfactorily.
Isobutyric acid volatilizes only to a low degree from water.
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