Registration Dossier
Registration Dossier
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EC number: 204-812-8 | CAS number: 126-92-1
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Readily biodegradable according to OECD criteria: 89.3% after 28 days based on CO2 evolution (OECD 301 B).
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
The key, GLP test was performed according to OECD guideline 301 B (Brunswik-Titze, 2003). Activated, domestic, non-adapted sludge was used as inoculum and the initial concentration of the test substance was 20 mg/L expressed as organic carbon. CO2 evolution was measured for 28 days. Biodegradation reached 89.3% after 28 days and 79.6% after 10 days passing the 10-day window. It can be concluded that C8-isoAS Na (CAS 126-92-1) is readily biodegradable according to OECD criteria. The supporting GLP study performed according to EU Method C.4-4 is available (Diefenbach 1995). Activated, domestic, non-adapted sludge was used as inoculum and the initial concentration of the test substance was 14.19 mg/L as DOC after 3 hours. 97% of biodegradation as DOC removal was determined after 28 days and reached 94% after 10 days. Moreover a GLP study performed according to ISO 14593 guideline is present (Daniel 2006). Secondary effluent from a laboratory treatment unit, treating sewage of predominantly domestic origin was used as inoculum. The initial concentration of the test substance was 23.8 mg/L as TOC. The test substance was biodegraded by 99% after 28 days based on inorganic carbon analysis. An additional GLP biodegradation test was performed according to OECD guideline 301 E (Schöberl 1992). Domestic non-adapted sewage was used as inoculum and the initial concentration of the test substance was 11.2 mg/L as DOC. Biodegradation of 15% was determined after 28 days as DOC removal. The test report does not allow evaluating why such a low biodegradation was measured. Nevertheless, this result can be overruled by three good quality reports mentioned earlier proving ready biodegradability of C8-isoAS Na (CAS 126-92-1).
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