Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_environmental-fate-and-pathways.png)
Adsorption / desorption
Administrative data
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 02/12/2008 to 17/02/2009
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study conducted to GLP in accordance with recognised guideline
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC estimation method
- Media:
- soil/sewage sludge
Test material
- Details on test material:
- No further information required.
Constituent 1
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
Not applicable. - Radiolabelling:
- no
Study design
- Test temperature:
- no data available
HPLC method
- Details on study design: HPLC method:
- HPLC System: Agilent Technologies 1200, incorporating autosampler and workstation
Column: Zorbax SB-CN 5 µm (250 x 4.6 mm id)
Column temperature: 40°C
Mobile phase A: methanol: reverse osmosis water (55:45 v/v);
adjusted to pH 7, with 0.1M sodium hydroxide
pH of mobile phase: 7.1
Flow-rate: 1.0 ml/min
UV detector wavelength: dead time and reference standards: 210 nm sample: 269 nm
Injection volume: 10 µl
The retention times of formamide and the retention times, capacity factors (k) and log10 Koc values for the reference standards are shown in the two following tables:
Dead Time Retention Time (mins) Mean Retention Time(mins)
Injection 1 Injection 2
Formamide 2.826 2.833 2.830
Standard Retention Time (mins) Mean retention time (mins) Capacity Factor (k) Log10 k Log10 Koc
Injection 1 Injection 2
Acetanilide 3.844 3.845 3.845 0.359 -0.445 1.25
Phenol 3.691 3.690 3.691 0.304 -0.517 1.32
Isoproturon 5.699 5.673 5.686 1.01 4.13 x 10-3 1.86
Triadimenol 7.512 7.525 7.519 1.66 0.219 2.40
Naphthalene 6.813 6.805 6.809 1.41 0.148 2.75
Endosulfan-diol 9.259 9.271 9.265 2.27 0.357 3.02
Fenthion 11.541 11.533 11.537 3.08 0.488 3.31
a-Endosulfan 16.586 16.620 16.603 4.87 0.687 4.09
Diclofop-methyl 18.106 18.102 18.104 5.40 0.732 4.20
DDT 36.330 36.403 36.367 11.9 1.070 5.63
Batch equilibrium or other method
- Analytical monitoring:
- yes
- Details on sampling:
- Solutions of reference standards were prepared in methanol, see table:
Standard Purity** (%) Concentration (mg/l)
Acetanilide 99+ 104
Phenol 99+ 118
Isoproturon 99.8 100
Triadimenol 98.4 112
Naphthalene ≥99.0 110
Endosulfan-diol 99.8 105
Fenthion 97.8 126
a-Endosulfan 99.6 120
Diclofop-methyl 99.5 106
DDT 98 104
** value quoted by supplier
- Details on matrix:
- no data available
- Details on test conditions:
- As the test material was noted to contain numerous salted sulphonic acid groups, testing was carried out at pH 7, with the test material in its fully ionised state.
- Computational methods:
- The adsorption coefficient was calculated using the following equation:
Log10 Koc = (Log10 k-A)/B
Koc = adsorption coefficient
k = capacity factor
A = intercept of the calibration curve
B = slope of the calibration curve
Results and discussion
Adsorption coefficientopen allclose all
- Type:
- Koc
- Value:
- < 17.8
- Type:
- log Koc
- Value:
- < 1.25
Results: HPLC method
- Details on results (HPLC method):
- The dead time was determined by measuring the retention time of formamide (purity ≥99.5%, 1.02 x 10^3 mg/l solution in mobile phase).
HPLC System: Agilent Technologies 1100, incorporating autosampler and workstation
Column: Zorbax SB-CN 5 µm (250 x 4.6 mm id)
Column temperature: 40°C
Mobile phase A: methanol: reverse osmosis water (55:45 vlv);
adjusted to pH 7, with 0.1M sodium hydroxide
pH of mobile phase: 7.1
Flow-rate: 1.0 ml/min
UV detector wavelength: dead time and reference standards: 210 nm sample: 269 nm
Injection volume: 10 µl
The retention times of formamide and the retention times, capacity factors (k) and log10 Koc values for the reference standards are shown in the two following tables:
Dead Time Retention Time (mins) Mean Retention Time(mins)
Injection 1 Injection 2
Formamide 2.826 2.833 2.830
Standard Retention Time (mins) Mean retention time (mins) Capacity Factor (k) Log10 k Log10 Koc
Injection 1 Injection 2
Acetanilide 3.844 3.845 3.845 0.359 -0.445 1.25
Phenol 3.691 3.690 3.691 0.304 -0.517 1.32
Isoproturon 5.699 5.673 5.686 1.01 4.13 x 10-3 1.86
Triadimenol 7.512 7.525 7.519 1.66 0.219 2.40
Naphthalene 6.813 6.805 6.809 1.41 0.148 2.75
Endosulfan-diol 9.259 9.271 9.265 2.27 0.357 3.02
Fenthion 11.541 11.533 11.537 3.08 0.488 3.31
a-Endosulfan 16.586 16.620 16.603 4.87 0.687 4.09
Diclofop-methyl 18.106 18.102 18.104 5.40 0.732 4.20
DDT 36.330 36.403 36.367 11.9 1.07 5.63
Any other information on results incl. tables
The retention times, capacity factors and log10Kocvalues determined for the sample are shown in the following table:
Injection | Retention Time | Capacity Factor (k) | Log10k | Log10Koc |
(mins) | ||||
1 | 1.654 | <0.359 | <-0.445 | <1.25 |
2 | 1.681 | <0.359 | <-0.445 | <1.25 |
Mean log10 Koc: <1.25
Adsorption coefficient: <17.8
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The adsorption coefficient (Koc) of the test material has been determined to be less than 17.8, log10 Koc <1.25.
- Executive summary:
In a determination of general physico-chemical properties study (Harlan project number: 0959/0224) the test material has been determined to to have an adsorption coefficient of less than 17.8, log10 Koc <1.25.
The determination was carried out using the HPLC screening method, Method C19 Adsorption Coefficient of Commission Regulation (EC) No 440/2008 of 30 May 2008.
As the test material was noted to contain numerous salted sulphonic acid groups, testing was carried out at pH 7, with the test material in its fully ionised state.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
![ECHA](/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/echa_logo.png)
Παρόλο που ο Οργανισμός παρέχει μεγάλο μέρος του διαδικτυακού περιεχομένου στη γλώσσα σας, ένα μέρος αυτής της σελίδας είναι μόνο στα αγγλικά. Περαιτέρω πληροφορίες για την πολύγλωσση πρακτική του ECHA.
Καλώς ήρθατε στον δικτυακό τόπο του ECHA. Η παρούσα ιστοθέση δεν υποστηρίζεται πλήρως από τον Internet Explorer 7 (ή προγενέστερες εκδόσεις). Αναβαθμίστε τον φυλλομετρητή σας Internet Explorer σε πιο πρόσφατη έκδοση.
Ο παρών ιστότοπος χρησιμοποιεί cookies για να διασφαλίζεται ότι αποκομίζετε την καλύτερη δυνατή εμπειρία από την περιήγησή σας στους ιστοτόπους μας.
Μάθετε περισσότερα σχετικά με τον τρόπο που χρησιμοποιούμε τα cookies.