Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
toxicity to reproduction
Remarks:
other: read across
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2016
Report date:
2016

Materials and methods

Test guideline
Guideline:
other: read across
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-phenyl-2-imidazoline
EC Number:
213-313-4
EC Name:
2-phenyl-2-imidazoline
Cas Number:
936-49-2
Molecular formula:
C9H10N2
IUPAC Name:
2-phenyl-4,5-dihydro-1H-imidazole

Test animals

Species:
rat
Sex:
not specified

Administration / exposure

Route of administration:
oral: gavage
Duration of treatment / exposure:
see study report

Results and discussion

Results: P0 (first parental generation)

Effect levels (P0)

Key result
Dose descriptor:
NOAEL
Effect level:
69 mg/kg bw/day (nominal)
Based on:
test mat.
Sex:
not specified
Basis for effect level:
clinical signs

Results: F1 generation

Effect levels (F1)

Key result
Dose descriptor:
NOAEL
Generation:
F1
Effect level:
69 mg/kg bw/day
Based on:
test mat.
Sex:
not specified
Basis for effect level:
clinical signs

Overall reproductive toxicity

Reproductive effects observed:
not specified

Applicant's summary and conclusion