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EC number: 225-862-7 | CAS number: 5124-25-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1993
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- other: EG C.8 (Uber MITI-Test)
- Deviations:
- not specified
- Principles of method if other than guideline:
- In-house SOP A15
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- No data
- Duration of test (contact time):
- 5 d
- Details on study design:
- No data
- Preliminary study:
- No data
- Test performance:
- No data
- Parameter:
- BOD5
- Value:
- 10 mg O2/g test mat.
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- BOD5 of test substance was found to be 10 mg O2/g.
- Executive summary:
BOD5 of FAT 36014/F was determined according to in-house Ciba Geigy Methode A.15, which is comparable to internationally accepted guidelines. Based on these investigations, the BOD5 of test substance was found to be 10 mg O2/g. Considering the COD value determined with the test substance which is 1412 mg O2/g, the resulting BOD5/COD quotient is 0.007, indicating that the test substance is unlikely to be biodegradable.
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1993
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
- Deviations:
- yes
- Remarks:
- (instead of 28 d the test has been finished after 14 d since no degradation activity could be observed)
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Code number: FAT 36014/F
EN/Batch: 292347.26
Purity: 90.7 %
Appearance: solid
Solubility: <1 g/L (in water)
Storage: room temperature
Expiration date: 04/98 - Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, domestic (adaptation not specified)
- Details on inoculum:
- Strain / Inoculation: Mixture of polyvalent bacteria collected in the aeration tank of a domestic sewage treatment plant, ARA Basel Communal
Bacteria concentration: 30 mg/L - Duration of test (contact time):
- 14 d
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Reference substance:
- benzoic acid, sodium salt
- Preliminary study:
- No data
- Test performance:
- No data
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 14 d
- Details on results:
- The biodegradation of test substance (corrected by the innoculum control) expressed as the % of BOD versus ThOD was 0 % (14 d).
- Results with reference substance:
- The biodegradation (corrected by the inoculum control) expressed as the % of BOD versus ThOD was 91 % (14 d).
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- Under the study conditions, the test substance was not readily biodegradable.
- Executive summary:
The ready biodegradability of the test substance (of ca. 90.75 % purity) was determined in a 14 d MITI test (I) according to OECD Guideline 301C and the EU Method C.7.
Both the test substance and reference substance sodium benzoate were tested at a concentration of 100 mg/L. Biodegradation was equivalent to 0 and 91 %, respectively.
Under the study conditions, the test substance was not readily biodegradable.
- Endpoint:
- biodegradation in water: screening test, other
- Remarks:
- COD
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1993
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.6 (Degradation: Chemical Oxygen Demand)
- Version / remarks:
- DEV DIN 38'409 - H 41-1 (1980) corresponding to 92 / 96 / EEC C.6.
- Deviations:
- yes
- Remarks:
- Mean of 2 determinations instead of 3
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Code number: 36014/F
EN/Batch: 292347.26
Purity: 90.7 %
Appearance: solid
Solubility: <1 g/L (in water)
Storage: Room temperature
Expiration date: 04/98 - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- None
- Duration of test (contact time):
- 2 h
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Experimental conditions:
Sample weight: 7.39 ± 7.11 mg of the test substance
Temperature: 148 ± 3 °C
Duration: 2 hours
Estimation Technique: Titration (Potentiometric) METROHM Titroprozessor 670 (SAV : 00 111) - Reference substance:
- other: Potassium hydrogen phthalate solution
- Preliminary study:
- None
- Test performance:
- None
- Remarks on result:
- not measured/tested
- Details on results:
- None
- Parameter:
- COD
- Value:
- 1 412 mg O2/g test mat.
- Results with reference substance:
- The COD of Potassium hydrogen phthalate is (Criteria: 200 ± 8 mg O2/I): 201 mg O2/I
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- The COD of FAT-36014/F was found to be 1412 mg O2/g. The COD of the reference substance (potassium hydrogen pthalate) was found to be 201 mg O2/I
- Executive summary:
A test was carried out according to DEV DIN 38'409 - H 41-1 (1980) corresponding to 92/96/EEC C.6. The test was performed in compliance with the Good Laboratory Practice (GLP) Regulations of Switzerland.
A predeterminated amount of the test substance FAT - 36014/F in water is oxidized by potassium dichromate in a strong sulphuric acid medium with silver sulphate as a catalyst under reflux for 2 hours. The residual dichromate is determined by titration with standardized ferrous ammonium sulphate.
The test substance was tested with a sample weight of 7.39 ± 7.11 mg. The reference substance Potassium hydrogen phthalate solution was tested in a concentration of 20 ml/I.
Based on the findings of the test, the COD of FAT-36014/F was calculated to be 1412 mg O2/g. The COD of the reference substance (potassium hydrogen pthalate) was found to be 201 mg O2/I.
Referenceopen allclose all
Description of key information
The test item FAT 36014 was investigated for its ready biodegradability following OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I)). In this study both the test substance and reference substance sodium benzoate were tested at a concentration of 100 mg/L. Biodegradation was equivalent to 0 % and 91 %, respectively. Another test to determine the COD value was performed following EU Method C.6. The test substance was tested with a sample weight of 7.39 ± 7.11 mg. The reference substance potassium hydrogen phthalate solution was tested in a concentration of 20 ml/l. The COD of FAT-36014/F was found to be 1412 mg O2/g in comparison with the COD of the reference substance 201 mg O2/l. At the end of 44 days a study conducted following OECD Guideline 302 B (Inherent biodegradability: Zahn-Wellens/EMPA Test) found 59 % elimination. Few more studies rated as weight of evidence with Klimisch 4 reported COD: 1412 mg/O2 g, percent degradation in 14 days: 0 %. In the light of percentage degradation and COD data from all the above mentioned studies the test item FAT 36014 is considered as not biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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