Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 950-463-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- Principles of method if other than guideline:
- not applicable
- GLP compliance:
- yes
- Type of method:
- other: Knudsen cell effusion method
- Specific details on test material used for the study:
- Name: HESI0108
Physical state: Light yellow liquid
Sponsor batch: 0008624816
Purity: 99.3 %
Arrival date: 14 December 2016
Expiry date: 25 August 2017
Storage conditions: Room temperature (15 to 30°C) - Key result
- Test no.:
- #1
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Key result
- Test no.:
- #2
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Conclusions:
- The vapour pressure of HES 10108 was evaluated using OECD guideline 104 and 44012008 EC Method A.4. (Knudsen cell effusion method):
Vapour pressure at 20°C = 2.2 x 10(-10) Pa Vapour pressure at 25°C =5.7 x 10(-10) Pa
The test substance was stable throughout the vapour pressure test. - Executive summary:
The vapour pressure of HES 10108 was evaluated using OECD guideline 104 and 44012008 EC Method A.4. (Knudsen cell effusion method):
Vapour pressure at 20°C = 2.2 x 10(-10) Pa Vapour pressure at 25°C =5.7 x 10(-10) Pa
The test substance was stable throughout the vapour pressure test.
Reference
Vapour Pressure
The thermal analysis revealed that HES 10108 was thermally stable up to 210°C.
Test 1
The temperature range for this test was 20 to 159°C, this established that the vapour pressure was too low to be measured below 96°C, after initial weight losses at the lower temperatures,
possibly due to solvent loss/impurities.
Test 2
The temperature range for this test was 125 to 156°C. The results from this test suggested that the results might be on the curved part of the Ln (VP) vs 1/T graph, which could possibly explain the results in Test 1.
Test 3
The temperature range was 94 to 131°C, this gave rise to some quite erratic results, the initial loss at 94°C was due to the same reasons as in Test 1, the temperature was increased when the vapour pressure went below 1 x 10 (-4) Pa.
To exclude outside factors influencing the results; dioctyl phthalate was tested over a similar range to that of this test. This would check that the system pressure display was correct. The vapour pressure at 20°C was 5.9 x 10-6 Pa, compared to 5.9 x 10-6 Pa cited in OPPTS 830.7950. This confirmed that the system pressure display was working correctly.
Test 4 The temperature range was 93 to 123°C. Once the vapour pressure at 93°C had dropped below 1 x 10 (-4) Pa; tests were performed over longer test periods than the previous tests in an attempt to improve consistency. The results for this test were also erratic.
Summary
The results from all the above tests were pooled for temperatures from 96°C (Test 1), 94°C (Test 3) and 94°C (Test 4) where the vapour pressure was lower than 1 x 10 (-4) Pa and then all temperatures up to 159°C for all the tests regardless of the vapour pressure. The combined results gave a good spread of results; from which the vapour pressure at 20 and 25°C could be estimated:
Vapour pressure at 20°C =2.2 x 10(-10) Pa Vapour pressure at 25°C = 5.7 x 10 (-10) Pa
Due to the uncertainty of measurement the accuracy of this result is ±50%, reflecting the nature of a complex mixture of components. IR analysis was performed only at the end of Test 4 and confirmed no degradation over the course of the test this was considered to be indicative of Tests 1 to 3.
Description of key information
The vapour pressure of HES 10108 was evaluated using OECD guideline 104 and 44012008 EC Method A.4. (Knudsen cell effusion method):
Vapour pressure at 20°C = 2.2 x 10(-10) Pa Vapour pressure at 25°C =5.7 x 10(-10) Pa
The test substance was stable throughout the vapour pressure test.
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.