Registration Dossier
Registration Dossier
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EC number: 700-330-1 | CAS number: 433733-92-7
Explosiveness
Administrative data
Link to relevant study record(s)
- Endpoint:
- explosive properties of explosives
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- key study
- Study period:
- 05 May - 15 October 2008
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.14 (Explosive properties)
- Deviations:
- no
- GLP compliance:
- yes
- Key result
- Parameter:
- other: Explosive (not specified)
- Remarks on result:
- negative (not further specified)
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The molecular structure of the test substance does not contain any chemically instable or highly energetic groups that might lead to an explosion. The impurities, present for < 0.3% in the test substance, were not taken into account but it is not to be expected that these have any influence.
Anhydrothymidine is not explosive.
Reference
The molecular structure of the test substance does not contain any chemically instable or highly energetic groups that might lead to an explosion.
Using C10H12N2O5 as molecular formula and 240.2 g/mol as molecular weight, the oxygen balance for the test substance was calculated to be –140%. This is > –200% and therefore within the region where there may be a potential for explodability. However, there are no plosophores (bond groupings known to give explosive properties) or auxoploses (explosive enhancing groups) present in the structure. The relatively high oxygen balance is considered due to the presence of a keton group, hydroxyl groups and a cyclic ether five-ring in the molecular structure of the test substance. Overall consideration of the properties does not suggest a risk of explodability.
Description of key information
The molecular structure of the test substance does not contain any chemically instable or highly energetic groups that might lead to an explosion. The impurities, present for < 0.3% in the test substance, were not taken into account but it is not to be expected that these have any influence.
Anhydrothymidine is not explosive.
Key value for chemical safety assessment
- Explosiveness:
- non explosive
Additional information
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
