Registration Dossier
Registration Dossier
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EC number: 444-110-0 | CAS number: 16510-27-3
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2002
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 002
- Report date:
- 2002
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method)
- GLP compliance:
- yes
- Test type:
- acute toxic class method
- Limit test:
- yes
Test material
- Reference substance name:
- -
- EC Number:
- 444-110-0
- EC Name:
- -
- Cas Number:
- 16510-27-3
- Molecular formula:
- C11H14O
- IUPAC Name:
- 1-(cyclopropylmethyl)-4-methoxybenzene
- Details on test material:
- Batch number LDP0200015
Purity 99.1%
Constituent 1
Test animals
- Species:
- rat
- Strain:
- other: Rat, HanBrl: Wist (SPF)
- Sex:
- male/female
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- polyethylene glycol
- Remarks:
- PEG 300
- Doses:
- signle dose at 2000 mg/Kg
- No. of animals per sex per dose:
- 3 males and 3 females
- Control animals:
- no
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The median lethal dose of Cyclopropyl Estragole after a single oral administration to rats of the both sexes, observed over a period of 14 days is:
LD50 (rat): Greater than 2000 mg/Kg Body weight
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