Propanoic acid, 2-[(ethoxythioxomethyl)thio]-, methyl ester

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 26 September 2000 to February 2001

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Reason / purpose for cross-reference:

reference to other study

Reason / purpose for cross-reference:

reference to other study

Reason / purpose for cross-reference:

reference to other study

Reason / purpose for cross-reference:

reference to other study

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

static method

Test no.:

#1

Temp.:

37 °C

Vapour pressure:

202.9 Pa

Test no.:

#2

Temp.:

40.8 °C

Vapour pressure:

611.2 Pa

Test no.:

#3

Temp.:

51 °C

Vapour pressure:

754.6 Pa

Test no.:

#4

Temp.:

30.8 °C

Vapour pressure:

229.6 Pa

Test no.:

#5

Temp.:

36 °C

Vapour pressure:

262 Pa

Test no.:

#6

Temp.:

45.5 °C

Vapour pressure:

325.5 Pa

The corrected vapour pressures were plotted in a Clausius-Clapeyron plot (log p [p in Pa] versus 1/T [T in K]). All the experimental data have been used for this regression.

Interpolation using this regression function yields an estimated vapour pressure of 108.9 Pa at 20°C and 150.9 at 25°C.

Conclusions:

The test item vapour pressure is estimated to be 108.9 Pa at 20°C and 150.9 Pa at 25°C.

Executive summary:

The test item vapour pressure was determined with the static method according to recognised guideline under GLP. No deviation from the guideline was observed in the study.

Experimental vapour pressures have been measured between 30.8°C and 51°C. The data obtained have been used to build a Clausius-Clapeyron plot (log p [p in Pa] versus 1/T [T in K]). All the experimental data have been used for this regression.

Interpolation using this regression function yields an estimated vapour pressure of 108.9 Pa at 20°C and 150.9 at 25°C.

Description of key information

The vapour pressure of the test item was determined in an experimental key study of Klimisch validity 1.

Key value for chemical safety assessment

Vapour pressure:

108.9 Pa

at the temperature of:

20 °C