Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
other information

Data source

Reference
Reference Type:
secondary source
Title:
No information
Bibliographic source:
ECHA database; http://apps.echa.europa.eu/registered/data/dossiers/DISS-9d91195a-65f3-618d-e044-00144f67d249/DISS-9d91195a-65f3-618d-e044-00144f67d249_DISS-9d91195a-65f3-618d-e044-00144f67d249.html

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
Deviations:
no
GLP compliance:
yes

Test material

Constituent 1
Reference substance name:
Automatically generated during migration to IUCLID 6, no data available
IUPAC Name:
Automatically generated during migration to IUCLID 6, no data available
Details on test material:
- Name of test material (as cited in study report): Secondary Butyl Alcohol

Test animals

Species:
rabbit

Test system

Type of coverage:
semiocclusive
Vehicle:
unchanged (no vehicle)

Results and discussion

In vivo

Resultsopen allclose all
Irritation parameter:
erythema score
Basis:
mean
Time point:
other: 4h, 24h, 48h, 72h and 7 days
Score:
0
Max. score:
4
Remarks on result:
other: All individual scores were 0 at all time-points indicated.
Irritation parameter:
edema score
Basis:
mean
Time point:
other: 4h, 24h, 48h, 72h and 7 days
Score:
0
Max. score:
4
Remarks on result:
other: All individual scores were 0 at all time-points indicated.

Applicant's summary and conclusion