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EC number: 939-448-5 | CAS number: 1469983-46-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
Link to relevant study record(s)
Description of key information
The adsorption coefficient (Kd) was determined in a test according to OECD TG 106. The Kd values are in the range of 940 – 2590 L/kg for three different soils. The mean value of 2010 L/kg will be used for risk assessment purposes. The substances will adsorp strongly onto the solid phase of soil and sediments due to the cationic surface-active properties. The substance can adsorb both onto the organic fraction and, dependent on the chemical composition, onto the surface of the mineral phase, where sodium and potassium ions can be exchanged against the alkyl ammonium ion. The determination of a Koc from log Kow is not opportune, because the common equations for Koc derivation is not valid for both ionic and surface active substances.
Key value for chemical safety assessment
Other adsorption coefficients
- Type:
- log Kp (solids-water in soil)
- Value in L/kg:
- 3.3
- at the temperature of:
- 22 °C
Other adsorption coefficients
- Type:
- log Kp (solids-water in suspended matter)
- Value in L/kg:
- 3.6
- at the temperature of:
- 22 °C
Other adsorption coefficients
- Type:
- log Kp (solids-water in sediment)
- Value in L/kg:
- 3.3
- at the temperature of:
- 22 °C
Additional information
The adsorption behaviour was studied in a batch equilibrium experiment according to a refined OECD TG 106 (GLP, Reliability 1). The sorption test was performed with the reaction mixture N-(3-(Tridecyloxy)propyl)-1,3-propane diamine, acetate and N-(3-(Tridecyloxy)propyl)- 1,3-propane diamine. The results have been read-across to the registered substance. The read-across is considered justified based on structural similarities and similar physical chemical properties. The test substance consists mainly of the etherdiamine with carbon chain lengths C12 and C13.
The sorption test was performed with three soils encompassing a range of % clay and organic matter.The test substance adsorbed partially onto the container walls which was considered for the determination of the adsorption coefficients.Adsorption kinetics were determined by measurements at different sampling times (up to 24 h), an equilibrium was reached after 3 hours. Desorption occurred to a lesser extent than adsorption. The table below presents a summary of the most important soil properties and observed partitioning constants.
Soil properties and related soil partitioning constants:
Soil |
Clay |
Silt |
Sand |
CEC |
pH |
Org C |
Caq |
Kd |
Koc |
(%) |
(%) |
(%) |
(meq/100g) |
(%) |
(µg/L) |
(102cm3/g) |
(104cm3/g) |
||
Speyer 2.2 |
6.4 |
11.6 |
82.0 |
10 |
5.5 |
2.09 |
33.9 |
9.4 |
4.5 |
Eurosoil 4 |
20.3 |
75.7 |
4.1 |
17.3 |
6.8 |
1.31 |
44.2 |
25.9 |
19.8 |
Speyer 6S |
42.7 |
36.1 |
22.2 |
22 |
7.2 |
1.69 |
95.7 |
25 |
14.8 |
From the data it can be observed that the sorption onto Speyer 6S is much higher than to Speyer 2.2 despite of the higher organic matter content in Speyer 2.2 soil. This can be explained by the fact that ionic interactions play a more important role than hydrophobic partitioning with organic matter. Alkyl ammonium ions can interact with the surface of mineral particles or with negative charges of humic substances.
The number of soils which was used in this test deviates from the recommendation in OECD guideline 106 (2000) in that three soils were used instead of the recommended five soils. In addition the partitioning to soil is not based on a Freundlich isotherm but evaluated based on only one test concentration. These deviations are based on results of earlier adsorption desorption tests with cationic surfactants. The amines in the test substance will to a large extent be protonated under ambient conditions and will therefore interact with the negative surface of mineral particles or with negative charges of humic substances. The ionic interactions play a more important role than hydrophobic partitioning with organic matter. The log Koc is therefore considered as a poor predictor of the partitioning behaviour of cationic surfactants in the environment. These earlier results showed that using three soils with at least one loamy sand and a clay soil, can give as much information as using the full number of soils. These earlier tests also revealed that only rarely linear adsorption isotherms were obtained for cationic surfactants and that extrapolation to lower concentrations based on these non-linear isotherms leads to unrealistic results (e.g. RAR primary fatty amines Oct. 2008). According to the Danish EPA (2004) a more reliable method of extrapolation to lower concentrations, is to use the data originating from the lowest measured concentration and to assume that the coefficient remains constant at lower concentrations. The test as described is therefore performed using only one concentration which is as low as reasonably possible in relation to the detection limit.
The initial concentration used for the determination of the soil partitioning constant were 0.26, 2.5 and 1 mg/L for respectively Speyer 2.2, S6 and Eurosoil 4. The observed aquatic equilibrium concentrations in the experiment range from 34 to 96 µg/L.
For the prediction of the partitioning of the etherdiamine in soil, sediment and suspended matter not the Kd based on organic matter will be used but the uncorrected Kd because the relation between the organic matter concentration and the sorption observed alone is not sufficient. Research sponsored by APAG CEFIC is currently performed at University of Leipzich (UFZ, K.U. Goss, S. Droge) and Utrecht (IRAS, J. Hermens) to improve the knowledge on bioavailability and partitioning to soil and sediment.
Because there is no principal difference between soil and sediments considering the sorption properties and because for cationic surfactants the degree of sorption is not related to the organic carbon content, the value for soil will also be used for sediment and suspended particles.
In table below the distribution constants used in this assessment is summarized:
Table. :Distribution constants for etherdiamine
Kpsoil |
2010 L.kg-1 |
Ksoil-water |
3015 m3.m-3 |
||||
Kpsusp |
4020 L.kg-1 |
Ksusp-water |
1005 m3.m-3 |
||||
Kpsed |
2010 L.kg-1 |
Ksed-water |
1005 m3.m-3 |
With a Kpsusp of 4020 L/kg and a concentration of 15 mg/L suspended matter in surface waters, the adsorbed fraction is calculated as ±7%.
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