3,5-dichloro-2,4-difluorobenzoyl fluoride

Guidance on Safe Use

First-aid measures

Inhalation: Get medical attention immediately. Move affected person to fresh air.

If it is suspected that fumes are still present, the rescuer should wear

an appropriate mask or self-contained breathing apparatus. Keep

person warm and at rest. If not breathing, if breathing is irregular or if

respiratory arrest occurs, provide artificial respiration or oxygen by

trained personnel. It may be dangerous to the person providing aid to

give mouth-to-mouth resuscitation. If unconscious, place in recovery

position and get medical attention immediately. Maintain an open

airway. Loosen tight clothing such as a collar, tie, belt or waistband.

After inhalation take calcium tablets as for skin contact. Treat with a

corticoid metered aerosol depending on the amount inhaled. If

appropriate symptoms occur or inhalation of large quantities is

suspected, administer cortisone intravenously in addition

Ingestion: Get medical attention immediately. Wash out mouth with water.

Move exposed person to fresh air. Keep person warm and at rest. If

material has been swallowed and the exposed person is conscious,

give small quantities of water to drink. Stop if the exposed person

feels sick as vomiting may be dangerous. Do not induce vomiting

unless directed to do so by medical personnel. If vomiting occurs,

the head should be kept low so that vomit does not enter the lungs.

Chemical burns must be treated promptly by a physician. Never give

anything by mouth to an unconscious person. If unconscious, place

in recovery position and get medical attention immediately. Maintain

an open airway. Loosen tight clothing such as a collar, tie, belt or waistband.

Skin contact: Get medical attention immediately. Flush contaminated skin with

plenty of water. Remove contaminated clothing and shoes. Continue

to rinse for at least 10 minutes. Chemical burns must be treated

promptly by a physician. In the event of any complaints or symptoms,

avoid further exposure. Wash clothing before reuse. Clean shoes

thoroughly before reuse.

Apply calcium gluconate gel to the affected area, rub in until locally

free of pain and then continue for further 15 minutes. If possible

apply a dressing soaked in 20% calcium gluconate solution. If burns

cover more than area of the hand ( = approx. 150 cm²)

6 effervescent calcium pills (400 mg calcium per pill) must be

dissolved in water and taken orally. This dose should be repeated

every 2 hours until the patient is in hospital. If burns cover large

areas patient should be completely bathed in at least 1% calcium

gluconate solution. If burns cover large areas patient should be

completely bathed in at least 1% calcium gluconate solution.

Eye contact: Get medical attention immediately. Immediately flush eyes with

plenty of water, occasionally lifting the upper and lower eyelids.

Check for and remove any contact lenses. Continue to rinse for at

least 10 minutes. Chemical burns must be treated promptly by a physician.

Fire-fighting measures

Extinguishing media

Suitable extinguishing media: Use dry chemical or CO2.

Unsuitable extinguishing media: Do not use water or foam.

Special hazards arising from the substance or mixture

Hazards from the substance or mixture: Contact with water liberates toxic gas. In a fire or if heated, a

pressure increase will occur and the container may burst.

Hazardous combustion products: Decomposition products may include the following materials:

carbon oxides

halogenated compounds

Advice for firefighters

Special precautions for firefighters: Promptly isolate the scene by removing all persons from the vicinity

of the incident if there is a fire. No action shall be taken involving any

personal risk or without suitable training. This material is harmful to

aquatic organisms. Fire water contaminated with this material must

be contained and prevented from being discharged to any waterway, sewer or drain.

Special protective equipment for fire-fighters:  Fire-fighters should wear appropriate protective equipment and selfcontained

breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

Accidental release measures

Personal precautions, protective equipment and emergency procedures: No action shall be taken involving any personal risk or without

suitable training. Evacuate surrounding areas. Keep unnecessary

and unprotected personnel from entering. Do not touch or walk

through spilt material. Keep away from water. Avoid breathing

vapour or mist. Provide adequate ventilation. Put on appropriate personal protective equipment.

Environmental precautions: Avoid dispersal of spilt material and runoff and contact with soil,

waterways, drains and sewers. Inform the relevant authorities if the

product has caused environmental pollution (sewers, waterways, soil

or air). Harmful to aquatic organisms, may cause long-term adverse

effects in the aquatic environment.

Methods and materials for containment and cleaning up:

Small spill: Stop leak if without risk. Move containers from spill area. Avoid

allowing the spilled material to get wet or using water to clean up

spillages or residues, unless the quantity remaining is very small.

Absorb with an inert material and place in an appropriate waste

disposal container. Dispose of via a licensed waste disposal contractor.

Large spill : Stop leak if without risk. Move containers from spill area. Prevent

entry into sewers, water courses, basements or confined areas.

Avoid allowing the spilled material to get wet or using water to clean

up spillages or residues, unless the quantity remaining is very small.

Contain and collect spillage with non-combustible, absorbent

material e.g. sand, earth, vermiculite or diatomaceous earth and

place in container for disposal according to local regulations. Dispose of via a licensed waste disposal contractor.

Contaminated absorbent material may pose the same hazard as the spilt product.

Handling and storage

Manufacture and use of this chemical intermediate takes place under strictly controlled conditions, as described in Art. 17/18 REACH. The substance is rigorously contained during manufacturing and use and appropriate risk management measures including PPE (i.g. during charging or sampling) are applied. Occupational exposure is reduced to a minimum and well controlled by measurements. A management system covering all general aspectsof a chemical production is in place, especially cleaning and maintenance of plants and equipment. An authorisation scheme based on instructions covering the whole process ensures that only trained and authorised staff handles the substance.

Put on appropriate personal protective equipment.

Eating, drinking and smoking should be prohibited in areas where this

material is handled, stored and processed. Workers should wash

hands and face before eating, drinking and smoking. Persons with a

history of skin sensitization problems should not be employed in any

process in which this product is used. Do not get in eyes or on skin or

clothing. Do not breathe vapour or mist. Do not ingest. Use only with

adequate ventilation. Wear appropriate respirator when ventilation is

inadequate. Keep in the original container or an approved alternative

made from a compatible material, kept tightly closed when not in use.

Keep away from water. Empty containers retain product residue and

can be hazardous.

The product is registered with strictly controlled conditions as defined in Article 17(3) or 18(4) of the regulation

(EC) no. 1907/2006 (REACH regulation) and must therefore be handled as

such. Refer to the industry guidance prepared by Concawe/Cefic/

EFCG for advice on the confirmation of strictly controlled conditions.

Conditions for safe storage, including any incompatibilities

Do not store below the following temperature: -10°C (14°F). Store in

accordance with local regulations. Store in original container

protected from direct sunlight in a dry, cool and well-ventilated area,

away from incompatible materials and food and

drink. Keep away from water. Keep container tightly closed and

sealed until ready for use. Containers that have been opened must

be carefully resealed and kept upright to prevent leakage. Do not

store in unlabelled containers. Use appropriate containment to avoid

environmental contamination.

Seveso II Directive - Reporting thresholds (in tonnes)

Danger criteria

Category

H2: Acute toxicity 2 any route of entry or Acute toxicity 3 Inhalation/Dermal route of entry

Notification and MAPP threshold: 50

Safety report threshold: 200

C2: Toxic

Notification and MAPP threshold: 50

Safety report threshold: 200

C10ii: Liberates toxic gas in contact with water

Notification and MAPP threshold: 50

Safety report threshold: 200

Remarks : Ensure effective ventilation. Vent waste air only via suitable

separators or scrubbers. Take precautionary measures against

electrostatic discharges.

Transport information

Shipping

SpecialProvisions

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

Shipping

Remarks

Shipping

Remarks

SpecialProvisions

Exposure controls / personal protection

Control parameters

Exposure limit values : Not available.

Recommended monitoring procedures:If this product contains ingredients with exposure limits, personal,

workplace atmosphere or biological monitoring may be required to

determine the effectiveness of the ventilation or other control

measures and/or the necessity to use respiratory protective

equipment. Reference should be made to monitoring standards,

such as the following: European Standard EN 689 (Workplace

atmospheres - Guidance for the assessment of exposure by

inhalation to chemical agents for comparison with limit values and

measurement strategy) European Standard EN 14042 (Workplace

atmospheres - Guide for the application and use of procedures for

the assessment of exposure to chemical and biological agents)

European Standard EN 482 (Workplace atmospheres - General

requirements for the performance of procedures for the

measurement of chemical agents) Reference to national guidance

documents for methods for the determination of hazardous substances will also be required.

Exposure controls

Risk management measures

Occupational exposure controls

Technical measures:

The substance shall be rigorously contained by technical means

during its whole lifecycle including manufacture, purification,

cleaning and maintenance of equipment, sampling, analysis,

loading and unloading of equipment or vessels, waste disposal or

purification and storage. Procedural and control technologies shall

be used that minimise emission and any resulting exposure. In

cases of accident and where waste is generated, procedural and/

or control technologies shall be used to minimise emissions and

the resulting exposure during purification or cleaning and

maintenance procedures.

Organisational measures:

Only properly trained and authorised personnel should handle the

substance. In the case of cleaning and maintenance works,

special procedures such as purging and washing shall be applied

before the system is opened and entered.

Personal protection measures

Respiratory protection:

If exposure cannot be ruled out, e.g. during product transfer,

sampling or maintenance, a well-fitting respiratory mask

conforming to standards or well-fitting respiratory device conforming to standards must be worn.  Respirator selection must

be based on known or anticipated exposure levels, the hazards of

the product and the safe working limits of the selected respirator.

Recommended: Full mask with type ABEK filter. Wear breathing apparatus with separate air supply (compressed air

respirator, tube apparatus) at higher concentrations.

Hand protection:

Chemical-resistant, impervious gloves complying with an approved

standard should be worn at all times when handling chemical

products if product contact cannot be excluded. After

contamination with product change the gloves immediately and

dispose of them according to relevant national and local

regulations

Recommended: (< 1 hour) Butyl rubber - IIR , Fluorinated rubber -

FKM or polyvinyl chloride (PVC)

Eye protection:

Safety eyewear complying with an approved standard should be

used to avoid exposure to liquid splashes, mists, gases or dusts.

Recommended: safety glasses with side-shields

Skin protection:

Wear protective clothing. Personal protective equipment for the

body should be selected based on the task being performed and

the risks involved and should be approved by a specialist before

handling this product.

Recommended: Recommended: Wear protective clothing.

Hygiene measures : Wash hands, forearms and face thoroughly after handling

chemical products, before eating, smoking and using the lavatory

and at the end of the working period. Appropriate techniques

should be used to remove potentially contaminated clothing. Wash

contaminated clothing before reusing. Ensure that eyewash

stations and safety showers are close to the workstation location.

Environmental exposure controls

Technical measures : Emissions from ventilation or work process equipment should be

checked to ensure they comply with the requirements of

environmental protection legislation. In some cases, fume

scrubbers, filters or engineering modifications to the process

equipment will be necessary to reduce emissions to acceptable levels.

Stability and reactivity

Reactivity: No specific test data related to reactivity available for this product or

its ingredients.

Chemical stability: The product is stable.

Possibility of hazardous reactions:

Hazardous reactions or instability may occur under certain conditions

of storage or use.

Conditions may include the following:

contact with water

Reactions may include the following: liberation of toxic gas

Conditions to avoid : Incompatibility with various substances: water, alcohols, amines,

mercaptanes, iron, aluminium and zinc. Compound decomposes in

the presence of water, therefore exclusion of moisture.

Incompatible materials : Reactive or incompatible with the following materials: Water

Hazardous decomposition products: Contact with water liberates toxic gas.

Disposal considerations

Waste treatment methods

Product

Methods of disposal:

Examine possibilities for re-utilisation. Product residues and

uncleaned empty containers should be packaged, sealed, labelled,

and disposed of or recycled according to relevant national and local

regulations. Where large quantities are concerned, consult the

supplier. When uncleaned empty containers are passed on, the

recipient must be warned of any possible hazard that may be caused

by residues. For disposal within the EC, the appropriate code

according to the European Waste List (EWL) should be used. It is

among the tasks of the polluter to assign the waste to waste codes

specific to industrial sectors and processes according to the

European Waste List (EWL).

Hazardous waste: The classification of the product may meet the criteria for a

hazardous waste.

Packaging

Methods of disposal:

The generation of waste should be avoided or minimised wherever

possible. Waste packaging should be recycled. Incineration or

landfill should only be considered when recycling is not feasible.

Special precautions:

This material and its container must be disposed of in a safe way.

Care should be taken when handling emptied containers that have

not been cleaned or rinsed out. Empty containers or liners may

retain some product residues. Avoid dispersal of spilt material and

runoff and contact with soil, waterways, drains and sewers.